Methylamino-PEG4-acid

Product Name: Methylamino-PEG4-acid
CAS No.: 1283658-71-8
Chemical Name: Methylamino-PEG4-acid
Synonyms: CAS_1283658-71-8;Methylamino-PEG4-acid;Methylamino-PEG4-CH2CH2COOH;Methylamino-PEG4-acid HCl salt;Methylamino-PEG4-acid hydrochloride;4,7,10,13-Tetraoxa-16-azaheptadecanoic acid;5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic Acid
CBNumber: CB33054281
Molecular Formula: C12H25NO6
Formula Weight: 279.33
MOL File: 1283658-71-8.mol

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Methylamino-PEG4-acid Property

Boiling point:: 405.5±40.0 °C(Predicted)
Density: 1.093±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
solubility: Soluble in Water, DMSO
pka: 4.28±0.10(Predicted)
form: Viscous Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M563190
Product name: Methylamino-PEG4-acid
Packaging: 2.5mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M563190
Product name: Methylamino-PEG4-acid
Packaging: 5mg
Price: $65
Updated: 2021/12/16

BroadPharm

Product number: BP-22202
Product name: Methylamino-PEG4-acidHClsalt
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-22202
Product name: Methylamino-PEG4-acidHClsalt
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1537
Product name: Methylamino-PEG4-acid
Packaging: 100mg
Price: $623
Updated: 2021/12/16

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Methylamino-PEG4-acid Chemical Properties,Usage,Production

Description

Methylamino-PEG4-acid HCl salt is a PEG linker containing a carboxylic acid with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Methylamino-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methylamino-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylamino-PEG4-acid Suppliers

China 27 United Kingdom 1 United States 3 Global 31

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9975
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Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 17714375163
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Country: China
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Shanghai Jiange Chemical Co., Ltd.

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Changsha Bono New Materials Technology Co., Ltd.

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Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7869
Advantage: 58

1283658-71-8, Methylamino-PEG4-acidRelated Search:

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Methylamino-PEG4-acid

Methylamino-PEG4-acid HCl salt

CAS_1283658-71-8

4,7,10,13-Tetraoxa-16-azaheptadecanoic acid

Methylamino-PEG4-CH2CH2COOH

Methylamino-PEG4-acid hydrochloride

5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic Acid

1283658-71-8