THP-SS-PEG1-Tos

Product Name: THP-SS-PEG1-Tos
CAS No.: 1807512-37-3
Chemical Name: THP-SS-PEG1-Tos
Synonyms: THP-SS-PEG1-Tos;2-((2-((Tetrahydro-2H-pyran-2-yl)oxy)ethyl)disulfaneyl)ethyl 4-methylbenzenesulfonate;Ethanol, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]-, 1-(4-methylbenzenesulfonate)
CBNumber: CB33062684
Molecular Formula: C16H24O5S3
Formula Weight: 392.55
MOL File: 1807512-37-3.mol

More

Less

THP-SS-PEG1-Tos Property

Boiling point:: 539.4±50.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-22778
Product name: THP-SS-PEG1-Tos
Purity: 98%
Packaging: 100mg
Price: $220
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1855
Product name: THP-SS-PEG1-Tos
Packaging: 100mg
Price: $428
Updated: 2021/12/16

More

Less

THP-SS-PEG1-Tos Chemical Properties,Usage,Production

Description

THP-SS-PEG1-Tos is a cleavable linker containing a THP protecting group and a tosyl end group. Tos is a good leaving group by reacting with nucleophiles, The disulfide bonds can be cleaved by using Dithiothreitol (DTT) reagent.

Uses

THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

THP-SS-PEG1-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

THP-SS-PEG1-Tos Suppliers

China 17 United Kingdom 1 United States 3 Global 21

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
Fax: 0086-571-81131109
Email: sales@huarongpharm.com
Country: CHINA
ProdList: 3148
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1995
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9801
Advantage: 58

Shanghai Huici Pharmaceutical Technology Co., LTD

Tel: 133-31922809 19372841038
Email: lixing@pharmahuici.com
Country: China
ProdList: 845
Advantage: 58

Affinity（Wuhan）Ltd.

Tel: 15841022315
Email: sales@affinitytech.cn
Country: China
ProdList: 3000
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

Xinyanpomei

Tel: 15850660754
Email: 15850660754@163.com
Country: China
ProdList: 1204
Advantage: 58

1807512-37-3, THP-SS-PEG1-TosRelated Search:

THP-SS-alcohol THP-PEG3 THP-PEG8-Tos TETRAHYDROPYRANYLDIETHYLENEGLYCOL THP-PEG4 2-(TETRAHYDRO-2H-PYRAN-2-YLOXY)ETHANOL THP-SS-PEG1-t-butyl ester

THP-SS-PEG1-Tos

Ethanol, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]-, 1-(4-methylbenzenesulfonate)

2-((2-((Tetrahydro-2H-pyran-2-yl)oxy)ethyl)disulfaneyl)ethyl 4-methylbenzenesulfonate

1807512-37-3

C16H24O5S3