2-Bromoquinolin-8-ol
- Product Name
- 2-Bromoquinolin-8-ol
- CAS No.
- 139399-61-4
- Chemical Name
- 2-Bromoquinolin-8-ol
- Synonyms
- 2-Bromoquinolin-8-ol;8-Quinolinol, 2-bromo-
- CBNumber
- CB33064123
- Molecular Formula
- C9H6BrNO
- Formula Weight
- 224.05
- MOL File
- 139399-61-4.mol
2-Bromoquinolin-8-ol Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1622CC
- Product name
- 2-Bromoquinolin-8-ol
- Packaging
- 1g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 139399614
- Product name
- 2-Bromo-8-hydroxyquinoline
- Packaging
- 1g
- Price
- $462.46
- Updated
- 2021/12/16
- Product number
- CM122305
- Product name
- 2-bromoquinolin-8-ol
- Purity
- 95%
- Packaging
- 5g
- Price
- $608
- Updated
- 2021/12/16
- Product number
- CD11266085
- Product name
- 2-Bromoquinolin-8-ol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $644
- Updated
- 2021/12/16
- Product number
- A116240
- Product name
- 2-Bromoquinolin-8-ol
- Purity
- 95%
- Packaging
- 5g
- Price
- $664
- Updated
- 2021/12/16
2-Bromoquinolin-8-ol Chemical Properties,Usage,Production
Synthesis
139399-65-8
139399-61-4
To a 100 mL round bottom flask was added 2-bromo-8-acetoxyquinoline (1.8 g, 6.6 mmol), potassium hydroxide (1.1 g, 20 mmol) and 16 mL of ethanol. The reaction mixture was heated to 50°C with continuous stirring for 3 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. Water was added to the residue to obtain a clarified solution and the pH was adjusted to neutral with dilute hydrochloric acid. Subsequently, the aqueous phase was extracted with dichloromethane (CH2Cl2), the organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give 1.5 g of the white solid product 2-bromoquinolin-8-ol in 99% yield.
References
[1] Patent: CN108947898, 2018, A. Location in patent: Paragraph 0058; 0063; 0064
[2] Journal of Organic Chemistry, 2010, vol. 75, # 2, p. 424 - 433
[3] Monatshefte fuer Chemie, 1991, vol. 122, # 11, p. 935 - 942
2-Bromoquinolin-8-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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