ChemicalBook > CAS DataBase List > Iodoform

Iodoform

Product Name
Iodoform
CAS No.
75-47-8
Chemical Name
Iodoform
Synonyms
CHI3;TRIIODOMETHANE;CHIT1;CHIT;ioforme;Iodofrm;odoform;FLJ00314;IODOFORM;Jodoform
CBNumber
CB6854229
Molecular Formula
CHI3
Formula Weight
393.73
MOL File
75-47-8.mol
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Iodoform Property

Melting point:
119 °C
Boiling point:
218°C
Density 
4.008 g/mL at 25 °C(lit.)
refractive index 
1.4975 (estimate)
storage temp. 
-20°C
solubility 
chloroform: soluble5%
form 
Crystalline Powder
color 
Bright yellow to dark yellow
Odor
char. pungent odor
Water Solubility 
Insoluble. <0.1 g/100 mL at 24 ºC
Sensitive 
Light Sensitive
Merck 
14,5033
BRN 
1697010
Exposure limits
ACGIH: TWA 0.6 ppm
NIOSH: TWA 0.6 ppm(10 mg/m3)
Stability:
Stable. Incompatible with strong oxidizing agents, reducing agents. May explode when heated.
LogP
3.510 (est)
CAS DataBase Reference
75-47-8(CAS DataBase Reference)
NIST Chemistry Reference
Methane, triiodo-(75-47-8)
EPA Substance Registry System
Iodoform (75-47-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37-36/37/39-22-24/25
RIDADR 
UN 1851
OEB
B
OEL
TWA: 0.6 ppm (10 mg/m3)
WGK Germany 
3
RTECS 
PB7000000
13
TSCA 
Yes
HS Code 
29033990
Hazardous Substances Data
75-47-8(Hazardous Substances Data)
Toxicity
LD50 s.c. in mice: 1.6 mmoles/kg (Kutob, Plaa)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
109452
Product name
Iodoform
Purity
99%
Packaging
5g
Price
$42.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB2501721
Product name
Anti-CHIT1 antibody produced in goat
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
100μg
Price
$568
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB1402723
Product name
Monoclonal Anti-CHIT1 antibody produced in mouse
Purity
clone 1D11, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
109452
Product name
Iodoform
Purity
99%
Packaging
100g
Price
$84.9
Updated
2024/03/01
Alfa Aesar
Product number
A13664
Product name
Iodoform, 99%
Packaging
50g
Price
$41.9
Updated
2024/03/01
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Iodoform Chemical Properties,Usage,Production

Description

Iodoform is a stable, pale yellow crystalline solid. It is volatile with a characteristic pungent, unpleasant and penetrating odour, but with a sweetish taste. It is incompatible with strong oxidising agents, reducing agents, lithium, and metallic salts such as mercuric oxide, silver nitrate, strong bases, calomel, and tannin. Reports indicate that earlier iodoform was in use as a disinfectant and as an antiseptic or dressing and healing of wounds and sores for pets. Iodoform is the active ingredient in many antiseptic or dressing powders used for dogs and cats to prevent infection.

Chemical Properties

yellow solid with a characteristic pungent and

Chemical Properties

Iodoform is a yellow or greenish-yellow powder or crystalline solid that is volatile with steam and contains 96.69% iodine. It has a very characteristic pungent odor. An odor threshold of 0.005 ppm has been reported.

Uses

Iodoform has limited use as a chemical intermediate and for medicinal purposes as disinfectant and antiseptic and has been used in veterinary medicine.

Uses

Triiodomethane is a crystalline compound commonly used as a disinfectant. It can be used in the process of removing heavy metals such as mercury from fuids.

Uses

It is used as a topical anti-infective, applied to the skin.

Definition

A yellow crystalline compound made by warming ethanal with an alkaline solution of an iodide:
CH3CHO + 3I + 4OH → CHI3 +
HCOO + 3H2O
The reaction also occurs with all ketones of general formula CH3COR (R is an alkyl group) and with secondary alcohols CH3CH(OH)R. Iodoform is used as a test for such reactions (the iodoform reaction).

General Description

Bright yellow or yellow powder or crystals. Penetrating odor. Unctuous touch. Odor threshold 0.4 ppb.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Iodoform decomposes at high temperatures. Decomposes slowly in light at room temperature. Reacts violently with lithium. Is incompatible with mercuric oxide, calomel, silver nitrate, tannin, and balsam Peru. Is also incompatible with strong bases, strong oxidizing agents and magnesium. Vigorous reactions occur with acetone in the presence of solid potassium hydroxide or calcium hydroxide, hexamethylenetetramine at 352° F, mercury(I) fluoride and finely divided reduced silver.

Hazard

Irritant. Decomposes violently at 400F (204C).

Health Hazard

Iodoform causes central nervous system depression and damage to the kidneys, liver, and heart.

Fire Hazard

Literature sources indicate that Iodoform is nonflammable.

Biochem/physiol Actions

Iodoform is an iodine containing compound, which is used in antiseptic applications in the medical and veterinary medicine fields. Iodoform improves fermentation in the biomass ensilage conversion system by improving lactic acid production and inhibiting butyric fermentation.

Carcinogenicity

Iodoform has been included in the NCI daily bioassay program. According to their summary: the high and low time-weighted average daily dosages of iodoform were, respectively, 142 and 71 mg/kg for male rats, 55 and 27 mg/kg for female rats, and 93 and 47 mg/kg for male and female mice. A significant positive association between dosage and mortality was observed in male rats but not in female rats or in mice of either sex. Adequate numbers of animals in all groups survived sufficiently long to be at risk from late-developing tumors. No statistical significance could be attributed to the incidences of any neoplasms in rats or mice of either sex when compared to their respective controls. Under the conditions of this bioassay, no convincing evidence was provided for the carcinogenicity of iodoform in Osborne–Mendel rats or B6C3F1 mice.

Purification Methods

Crystallise it from MeOH, EtOH or EtOH/EtOAc. It is steam volatile. It is a disinfectant. [Beilstein 1 IV 97.]

Iodoform Preparation Products And Raw materials

Raw materials

Preparation Products

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Iodoform Suppliers

Wuhan kemike Biomedical Technology Co., Ltd
Tel
13163388153 13163388153
Email
yeqiu416@163.com
Country
China
ProdList
9886
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
anqing sinosynth new materials technology co,ltd
Tel
18055625120
Email
aqsinosynth@163.com
Country
China
ProdList
477
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from Iodoform manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Iodoform 75-47-8
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
R&D Scientific Inc.
Product
Iodoform 75-47-8
Price
US $490.00/Kg
Min. Order
0.100Kg
Purity
98
Supply Ability
1000 Kg
Release date
2024-10-04
Weijer International Trade (Hebei) Co., Ltd
Product
Iodoform 75-47-8
Price
US $1.00/kg
Min. Order
1kg
Purity
>99%
Supply Ability
2000T
Release date
2023-03-16

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