ChemicalBook > CAS DataBase List > 5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
- Product Name
- 5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
- CAS No.
- 215294-98-7
- Chemical Name
- 5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
- Synonyms
- X-34;X-34 >=90% (HPLC);Benzoic acid, 3,3'-(1,4-phenylenedi-2,1-ethenediyl)bis[6-hydroxy-;5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid);5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid)
- CBNumber
- CB33084790
- Molecular Formula
- C24H18O6
- Formula Weight
- 402.4
- MOL File
- 215294-98-7.mol
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5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid) Property
- Boiling point:
- 669.9±55.0 °C(Predicted)
- Density
- 1.448±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2.0mg/mL, clear
- form
- Solid
- pka
- 2.85±0.10(Predicted)
- color
- Light yellow to yellow
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5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid) Chemical Properties,Usage,Production
Biological Activity
Fluorescent, amyloid-specific dye', 'X-34 (1,4-bis(3-carboxy-4-hydroxyphenylethenyl)-benzene) is one among the small-molecule γ-secretase modulators (GSMs) involved in lowering Aβ42 levels (the 42-residue isoform of the amyloid-β peptide). X-34 has also been used to visualize intracellular immunoreactive deposits with classic amyloid fibrillar ultrastructure in living transgenic Caenorhabditis elegans animals. It is also used as a histochemical stain for determining pathological changes in Alzheimerμs disease (AD).', 'X-34 is a fluorescent, amyloid-specific dye. It binds at a different site than Pittsburgh Compound B and is a highly fluorescent marker for beta-sheet structures.
5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid) Preparation Products And Raw materials
Raw materials
Preparation Products
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5,5'-((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(2-hydroxybenzoic acid) Suppliers
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