Madrasin

Product Name: Madrasin
CAS No.: 374913-63-0
Chemical Name: Madrasin
Synonyms: CS-2251;Madrasin;DD00107587;DDD00107587;DDD-00107587;Madrasin >=98% (HPLC);Madrasin (DDD-00107587);DDD00107587;DD00107587;DDD-00107587;DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587;2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
CBNumber: CB33123143
Molecular Formula: C16H17N5O2
Formula Weight: 311.34
MOL File: 374913-63-0.mol

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Madrasin Property

storage temp.: 2-8°C
solubility: DMSO:1.5(Max Conc. mg/mL);4.82(Max Conc. mM)
form: powder
color: white to dark brown
InChI: 1S/C16H17N5O2/c1-8-9(2)17-16(20-14(8)22)21-15-18-10(3)12-6-5-11(23-4)7-13(12)19-15/h5-7H,1-4H3,(H2,17,18,19,20,21,22)
InChIKey: QQJIYKXTEMDJFM-UHFFFAOYSA-N
SMILES: CC1=NC(NC(NC(C)=C2C)=NC2=O)=NC3=CC(OC)=CC=C31

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1409
Product name: Madrasin
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $129
Updated: 2026/03/19

Sigma-Aldrich

Product number: SML1409
Product name: Madrasin
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $509
Updated: 2026/03/19

Cayman Chemical

Product number: 20451
Product name: Madrasin
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20451
Product name: Madrasin
Purity: ≥95%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 20451
Product name: Madrasin
Purity: ≥95%
Packaging: 10mg
Price: $169
Updated: 2024/03/01

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Madrasin Chemical Properties,Usage,Production

Uses

Madrasin has been used as a spliceosome inhibitor to inhibit pre-mRNA processing in 3T3-L1 cells.

Definition

ChEBI: 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-1H-pyrimidin-4-one is a member of quinazolines.

Biochem/physiol Actions

Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.

Madrasin Preparation Products And Raw materials

Raw materials

Preparation Products

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Madrasin Suppliers

China 72 India 1 United States 9 Global 82

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 88915
Advantage: 60

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 9697
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 7999
Advantage: 62

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 9955
Advantage: 58

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View Lastest Price from Madrasin manufacturers

Career Henan Chemical Co

Product: Madrasin 374913-63-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

374913-63-0, MadrasinRelated Search:

Madrasin

DD00107587

DDD00107587

DDD-00107587

DDD00107587;DD00107587;DDD-00107587

CS-2251

4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-

Madrasin >=98% (HPLC)

2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one

DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587

2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-5,6-dimethyl-3H-pyrimidin-4-one 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-4(1H)-pyrimidinone (9CI) 4(1H)-Pyrimidinone, 2-[(7-methoxy-4-methy

Madrasin (DDD-00107587)

374913-63-0

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