3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile

Uses

Product Name: 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
CAS No.: 1155846-86-8
Chemical Name: 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
Synonyms: MK -1439 intermediate;3-chloro-5-(2-oxo-6-(trifluoromethyl)-1,2-dihydropyridin-3-yloxy)benzonitrile;3-chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile;3-Chloro-5-{[2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]oxy}benzonitrile;3-Chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile;Benzonitrile, 3-chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]-
CBNumber: CB33123204
Molecular Formula: C13H6ClF3N2O2
Formula Weight: 314.65
MOL File: 1155846-86-8.mol

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3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile Property

Boiling point:: 409.4±45.0 °C(Predicted)
Density: 1.54±0.1 g/cm3(Predicted)
pka: 10.03±0.10(Predicted)
InChI: InChI=1S/C13H6ClF3N2O2/c14-8-3-7(6-18)4-9(5-8)21-11-10(13(15,16)17)1-2-19-12(11)20/h1-5H,(H,19,20)
InChIKey: HWTORHRJFMRBLG-UHFFFAOYSA-N
SMILES: C(#N)C1=CC(OC2=C(C(F)(F)F)C=CNC2=O)=CC(Cl)=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot

Product number: CD11345389
Product name: 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
Purity: 97%
Packaging: 1g
Price: $1340
Updated: 2021/12/16

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3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile Chemical Properties,Usage,Production

Uses

MK -1439 intermediate belongs to heterocyclic derivatives and can be used as pharmaceutical intermediates.

Description

3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile is a pharmaceutical intermediate compound, which can be used in the preparation of Doravirine. Doravirine is a non-nucleoside reverse transcriptase inhibitor that needs to be used in combination with other anti-HIV drugs for the treatment of patients who have not previously received HIV-1 antiretroviral therapy.

3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile Suppliers

China 35 India 3 United States 1 Global 39

Shanghai Boyle Chemical Co., Ltd.

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Chemvon Biotechnology Co., Ltd

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Changzhou Huanling Chemical Co., Ltd.

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AstaTech (Chengdu) Pharma. Co., Ltd.

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Shanghai Synchem Pharma Co., ltd

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Shanghai Chaolan Chemical Technology Center

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Capot Chemical Co.,Ltd.

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Henan Alpha Chemical Co., Ltd.

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Shanxi Xuanran Import and Export Trade Co., Ltd.

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Chongqing Chemdad Co., Ltd

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View Lastest Price from 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: MK -1439 intermediate 1155846-86-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-18

Career Henan Chemical Co

Product: MK -1439 intermediate 1155846-86-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-20

1155846-86-8, 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrileRelated Search:

HUMAN MIDKINE

MK -1439 intermediate

Benzonitrile, 3-chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]-

3-Chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile

3-Chloro-5-{[2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinyl]oxy}benzonitrile

3-chloro-5-(2-oxo-6-(trifluoromethyl)-1,2-dihydropyridin-3-yloxy)benzonitrile

3-chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile

1155846-86-8

C13H6ClF3N2O2

intermediate