HUMAN MIDKINE

Description Source Background

Product Name: HUMAN MIDKINE
CAS No.: 170138-17-7
Chemical Name: HUMAN MIDKINE
Synonyms: MK;MNK;ARAP;DSMAX;SMAX3;NEGF-2;TRICK2;MIDKINE;TRAIL-R2;HUMAN MK
CBNumber: CB4172653
Formula Weight: 0
MOL File: Mol file

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HUMAN MIDKINE Property

storage temp.: −20°C
color: white
biological source: synthetic

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP3301
Product name: MIDKINE mouse
Purity: recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Packaging: 20μG
Price: $366
Updated: 2025/07/31

Sigma-Aldrich

Product number: SRP3114
Product name: Midkine human
Purity: recombinant, expressed in <I>E. coli</I>, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging: 20 μg
Price: $356
Updated: 2025/07/31

Sigma-Aldrich

Product number: M3441
Product name: Midkine, human
Purity: ≥90% (SDS-PAGE)
Packaging: 50μg
Price: $1130
Updated: 2022/05/15

Usbiological

Product number: 155875
Product name: Midkine
Packaging: 10ug
Price: $333
Updated: 2021/12/16

Usbiological

Product number: M3896-02
Product name: Midkine
Packaging: 25ug
Price: $340
Updated: 2021/12/16

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HUMAN MIDKINE Chemical Properties,Usage,Production

Biological Activity

Midkine, a heparin-binding growth factor, contains 121 amino acid residues with 5 disulfide bonds. It promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. The C-terminal portion contains the heparin-binding domain and the antigenicity and neurite-promoting sequences. Both the C- and N-terminals are necessary for the moleculeμs neurotrophic effects.

Description

Midkine Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 123 amino acids and having a molecular mass of 13.4kDa.
The Midkine is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Midkine (MK) is the product of a retinoic acid responsive gene, MK, and is a member of a family of heparin binding factors. It contains 121 amino acid residues including 10 conserved cysteine residues, all of which appear to be disulphide linked.
Midkine is expressed during embryogenesis, showing an expression pattern that suggests functions in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm-epithelial interaction.
The widespread downregulation of MK in the adult human is reverted in a number of cancers, in which polypeptides are able to act as both transforming growth factors and promoters of angiogenesis.
Midkine (MK), induces chemotaxis of human neutrophils and was found to trigger mobilization of intracellular calcium of these cells.
Midkine induces histamine release from rat peritoneal mast cells with a rapid response in a dose dependent manner.
Midkine is also a potent stimulator of collagen and glycosaminoglycan synthesis.

HUMAN MIDKINE Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMAN MIDKINE Suppliers

China 102 Germany 1 Japan 2 Switzerland 1 United States 8 Global 114

Shanghai Kanglang Biotechnology Co., Ltd.

Tel: 021-61998208 18217752821
Fax: 021-37680378
Email: sales@klbio.cn
Country: China
ProdList: 9621
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 18438616290
Email: lanwu@univ-bio.com
Country: China
ProdList: 24731
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Yaji Biological Technology Co., Ltd.

Tel: 021-34661275 15301693058
Email: yajikit@163.com
Country: China
ProdList: 9897
Advantage: 58

Biolab Reagents

Tel: 027-65279366 18108604356
Email: products@biolabreagent.com
Country: China
ProdList: 9868
Advantage: 58

Nanjing Anyan Biological Technology Co., Ltd.

Tel: 025-52151215 13915956535 13915956535
Email: 570945402@qq.com
Country: China
ProdList: 9733
Advantage: 58

Beijing Boorsen Biotechnology Co., Ltd

Tel: 400-901-9800 18611424007
Email: cis@bioss.com.cn
Country: China
ProdList: 9518
Advantage: 58

ACROBiosystems

Tel: 13121935750
Email: jiaxin.zhao@acrobiosystems.com
Country: China
ProdList: 1354
Advantage: 58

ZSGB-BIO

Tel: 02-400-810-9781 400810978
Email: sales@zsbio.com
Country: China
ProdList: 2887
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

170138-17-7, HUMAN MIDKINERelated Search:

1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Aluminum acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Benzyl isocyanide TERT-BUTYL ISOCYANIDE SALCOMINE Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE Cupric acetylacetonate Tosylmethyl isocyanide METHYL ISOCYANOACETATE Ethyl isocyanoacetate Ferric acetylacetonate PHENYLSELENOL 2,4-PENTANEDIONE, SILVER DERIVATIVE COBALT(II) ACETYLACETONATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)

HUMAN MK

HUMAN NEGF-2

HUMAN MIDKINE

LYS-LYS-LYS-ASP-LYS-VAL-LYS-LYS-GLY-GLY-PRO-GLY-SER-GLU-CYS-ALA-GLU-TRP-ALA-TRP-GLY-PRO-CYS-THR-PRO-SER-SER-LYS-ASP-CYS-GLY-VAL-GLY-PHE-ARG-GLU-GLY-THR-CYS-GLY-ALA-GLN-THR-GLN-ARG-ILE-ARG-CYS-ARG-VAL-PRO-CYS-ASN-TRP-LYS-LYS-GLU-PHE-GLY-ALA-ASP-CYS-LYS-TYR-LYS-PHE-GLU-ASN-TRP-GLY-ALA-CYS-ASP-GLY-GLY-THR-GLY-THR-LYS-VAL-ARG-GLN-GLY-THR-LEU-LYS-LYS-ALA-ARG-TYR-ASN-ALA-GLN-CYS-GLN-GLU-THR-ILE-ARG-VAL-THR-LYS-PRO-CYS-THR-PRO-LYS-THR-LYS-ALA-LYS-ALA-LYS-ALA-LYS-LYS-GLY-LYS-GLY-LYS-ASP

RECOMBINANT HUMAN MIDKINE

MK

MIDKINE

MIDKINE, HUMAN

heparin-binding growth/differentiation factor

Anti-Mevalonate Kinase antibody produced in rabbit

TRAIL-R2

MIDKINE mouse

NEGF-2

TRICK2

Midkine, human >=90% (SDS-PAGE)

Rabbit Anti-Midkine antibody

DSMAX

MNK

SMAX3

ARAP

170138-17-7

BioChemical

Cell Biology

Chemokines

Cell Signaling and Neuroscience

Cytokines and Growth Factors

Cytokines, Growth Factors and Hormones