ChemicalBook > CAS DataBase List > 6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione

6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione

Product Name
6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione
CAS No.
1922954-32-2
Chemical Name
6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione
Synonyms
Palbociclib Impurity J;Palbociclib Impurity 83;Palbociclib impurity 09;6-Bromo-8-cyclopentyl-5-methylquinazoline-2,7(3H,8H)-dione;6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione;6-bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one;Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-bromo-8-cyclopentyl-5-methyl-;Palbociclib impurity 36/2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one;6-Bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity);Palbociclib Impurity 36/2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one/6-Bromo-8-cyclopentyl-5-methylquinazoline-2,7(3H,8H)-dione
CBNumber
CB33127671
Molecular Formula
C13H14BrN3O2
Formula Weight
324.17
MOL File
1922954-32-2.mol
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6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione Property

Density 
1.77±0.1 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
9.82±0.60(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione Chemical Properties,Usage,Production

Uses

6-Bromo-8-cyclopentyl-5-methylquinazoline-2,7(3H,8H)-dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.

6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione Suppliers

China 39 India 2 Global 41
Adamas Reagent, Ltd.
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400-6009262 15618770481
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021-64823266
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China
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Quality Control Solutions Ltd.
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0755-66853366 13670046396
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0755-28363542
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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051085625359
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sales@reading-chemicals.com
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Shanghai SuperLan Chemcial Technique Centre
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0-2022843681 15618226720
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+86-21-51601218
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Amadis Chemical Company Limited
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571-89925085
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Shanghai Zhen Li Biological Technology Co., Ltd
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021-16621358918; 18516310516
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13045646768
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XinYao(Shenzhen) Biological Technology Co., Ltd.
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0755-89880280
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Shenzhen Botel Biotechnology Co. Ltd.
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13316949107 13316968096
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ANHUI WITOP BIOTECH CO., LTD
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Yangzhou Changhua Biotechnology Co., Ltd.
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1922954-32-2, 6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dioneRelated Search:

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Palbociclib Impurity N Palbociclib Impurity D Palbociclib Impurity 21 Palbociclib impurity L Palbociclib Impurity H Palbociclib Impurity 38 di-tert-butyl 4,4'-(pyridine-2,5-diyl)bis(piperazine-1-carboxylate) tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Palbociclib Impurity 7 2324831-15-2 Palbociclib Impurity O Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- Palbociclib Impurity S 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester 5-(piperazin-1-yl)pyridin-2-aMine Palbociclib Impurity V

  • Palbociclib Impurity J
  • 6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione
  • Palbociclib impurity 36/2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione, 6-bromo-8-cyclopentyl-5-methyl-
  • 6-Bromo-8-cyclopentyl-5-methylquinazoline-2,7(3H,8H)-dione
  • 6-Bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one (Palbociclib Impurity)
  • 6-bromo-8-cyclopentyl-2-hydroxy-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • Palbociclib impurity 09
  • Palbociclib Impurity 83
  • Palbociclib Impurity 36/2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one/6-Bromo-8-cyclopentyl-5-methylquinazoline-2,7(3H,8H)-dione
  • 1922954-32-2