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ChemicalBook > CAS DataBase List > 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

Use
Product Name
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
CAS No.
1016636-76-2
Chemical Name
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
Synonyms
6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one;6-broMo-2-chloro-8-cyclopentyl-5-;6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one;PALBOCI;PALBOCICLIB-PB3;Palbociclib-015;Palbociclib nuclear;Pabucilib impurity 8;Palbociclib Impurity I;Palbociclib Intermediate 3
CBNumber
CB32554175
Molecular Formula
C13H13BrClN3O
Formula Weight
342.62
MOL File
1016636-76-2.mol
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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Property

Melting point:
190-192°C
Boiling point:
468.4±45.0 °C(Predicted)
Density 
1.645±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
-0.61±0.20(Predicted)
color 
White
InChI
InChI=1S/C13H13BrClN3O/c1-7-9-6-16-13(15)17-11(9)18(12(19)10(7)14)8-4-2-3-5-8/h6,8H,2-5H2,1H3
InChIKey
HJQCAEDIUJXGCQ-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C2C(C)=C(Br)C(=O)N(C3CCCC3)C2=N1
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN2811
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B682195
Product name
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
Packaging
100mg
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
096533
Product name
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
Purity
95+%
Packaging
250mg
Price
$742
Updated
2021/12/16
AK Scientific
Product number
J52040
Product name
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
Packaging
1g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
096533
Product name
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
Purity
95+%
Packaging
1g
Price
$1647
Updated
2021/12/16
AK Scientific
Product number
J52040
Product name
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
Packaging
10g
Price
$42
Updated
2021/12/16
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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties,Usage,Production

Use

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

Uses

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Suppliers

TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60182192,1339732154 18722583064
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
112
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61
Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
Email
saleskc@scipharmacn.com
Country
China
ProdList
684
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58
Shanghai Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
021-58955996
Email
info@chemexpress.com
Country
China
ProdList
755
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58
hongqing Huafeng Pharmaceutical Technology Co., LTD
Tel
023-67950001 13883380852
Fax
023-68265899
Email
cqhfyy@foxmail.com
Country
China
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Jinan Dexinjia Bio&Tech Co., Ltd
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0531-82375886 13001715031
Fax
0531-82375893
Email
3517280075@qq.com
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China
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1274
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CHONGOINGJICHENG BIOPHARMACEUTICAL SCIENCE AND TECHNOLOGY CO.. LTD
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023-67646862 18983213987
Email
cqlcg@foxmail.com
Country
China
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HONEST PHARM CO.,LTD.
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0531-59840128 19353175568
Fax
QQ:3379530787
Email
zpy8217@163.com
Country
China
ProdList
507
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Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
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55
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
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57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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View Lastest Price from 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one manufacturers

Nanjing Fred Technology Co., Ltd
Product
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-28
hebei hongtan Biotechnology Co., Ltd
Product
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-17
WUHAN FORTUNA CHEMICAL CO., LTD
Product
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
100kg
Release date
2021-11-03

1016636-76-2, 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-oneRelated Search:


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