ChemicalBook > CAS DataBase List > 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
Use- Product Name
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- CAS No.
- 1016636-76-2
- Chemical Name
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- Synonyms
- 6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one;6-broMo-2-chloro-8-cyclopentyl-5-;6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one;PALBOCI;PALBOCICLIB-PB3;Palbociclib-015;Palbociclib nuclear;Pabucilib impurity 8;Palbociclib Impurity I;Palbociclib Intermediate 3
- CBNumber
- CB32554175
- Molecular Formula
- C13H13BrClN3O
- Formula Weight
- 342.62
- MOL File
- 1016636-76-2.mol
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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Property
- Melting point:
- 190-192°C
- Boiling point:
- 468.4±45.0 °C(Predicted)
- Density
- 1.645±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- -0.61±0.20(Predicted)
- color
- White
- InChI
- InChI=1S/C13H13BrClN3O/c1-7-9-6-16-13(15)17-11(9)18(12(19)10(7)14)8-4-2-3-5-8/h6,8H,2-5H2,1H3
- InChIKey
- HJQCAEDIUJXGCQ-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C2C(C)=C(Br)C(=O)N(C3CCCC3)C2=N1
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- B682195
- Product name
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 096533
- Product name
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $742
- Updated
- 2021/12/16
AK Scientific
- Product number
- J52040
- Product name
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 096533
- Product name
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1647
- Updated
- 2021/12/16
AK Scientific
- Product number
- J52040
- Product name
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
- Packaging
- 10g
- Price
- $42
- Updated
- 2021/12/16
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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties,Usage,Production
Use
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.
Description
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is a pharmaceutical intermediate that can be used to synthesize Palbociclib, an inhibitor of cyclin-dependent kinases (CDKs) 4 and 6 for the treatment of breast cancer.
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Suppliers
- Tel
- +918790379245
- banny.janga@btcpharm.com
- Country
- India
- ProdList
- 1262
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
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View Lastest Price from 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2021-11-03
Nanjing Fred Technology Co., Ltd
- Product
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-28
hebei hongtan Biotechnology Co., Ltd
- Product
- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-17
1016636-76-2, 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-oneRelated Search:
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