Physical Form
ChemicalBook > CAS DataBase List > tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Physical Form
Product Name
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
CAS No.
571188-59-5
Chemical Name
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Synonyms
1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE;OTAVA-BB;4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester;OTAVA-BB 1207229;1-Boc-4-(6-amino-3-pyridyl)piperazine;tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate;POB02;PALBOCICLIB4;Ribociclib-2;Palbociclib-11
CBNumber
CB62464781
Molecular Formula
C14H22N4O2
Formula Weight
278.35
MOL File
571188-59-5.mol
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tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Property

Melting point:
130-132℃
Boiling point:
454.1±45.0 °C(Predicted)
Density 
1.182
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Very Slightly)
form 
Solid
pka
7.36±0.26(Predicted)
color 
Dark Yellow
Sensitive 
Air Sensitive
InChI
InChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)
InChIKey
RMULRXHUNOVPEI-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1
LogP
1.6-1.8 at 35℃ and pH7-9
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4669
Product name
tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$66
Updated
2024/03/01
TCI Chemical
Product number
B4669
Product name
tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$239
Updated
2024/03/01
Alfa Aesar
Product number
H54315
Product name
4-(6-Amino-3-pyridyl)-1-Boc-piperazine, 97%
Packaging
1g
Price
$170.65
Updated
2024/03/01
Alfa Aesar
Product number
H54315
Product name
4-(6-Amino-3-pyridyl)-1-Boc-piperazine, 97%
Packaging
5g
Price
$673.65
Updated
2024/03/01
Alfa Aesar
Product number
H54315
Product name
4-(6-Amino-3-pyridyl)-1-Boc-piperazine, 97%
Packaging
250mg
Price
$57.6
Updated
2021/12/16
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tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Chemical Properties,Usage,Production

Physical Form

Solid

Uses

4-(6-Amino-3-pyridyl)-1-Boc-piperazine (tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate) is used as an organic chemical synthesis intermediate.

Preparation

4- (6-Nitro-pyridin-3-yl)-piperazine-1 -carboxylic acid ie f-butyl ester and Pd/C in ethanol is stirred with an H2 balloon for 3 h. The product tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is obtained through purification.

Hazard

Causes skin irritation
Causes serious eye irritation
May cause respiratory irritation

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Suppliers

TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
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022-60182192,1339732154 18722583064
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86-22-60979672
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marketing@pharmacn.com
Country
China
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Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
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saleskc@scipharmacn.com
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China
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hongqing Huafeng Pharmaceutical Technology Co., LTD
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023-67950001 13883380852
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023-68265899
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China
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Shandong Zhongke Taidou Chemical Co., Ltd.
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0531-88682302 18615650139
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0531-62325738
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3303447386@qq.com
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China
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0531-68657833 15553112864
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Shanghai Haoyuan Chemexpress Co., Ltd.
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021-58950125
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021-58955996
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info@chemexpress.com
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China
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HONEST PHARM CO.,LTD.
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QQ:3379530787
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zpy8217@163.com
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China
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18684929597
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527907673@qq.com
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China
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Shanghai Boyle Chemical Co., Ltd.
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86-21-57758967
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sales@boylechem.com
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China
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Chemvon Biotechnology Co., Ltd
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+86-21-50790419
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View Lastest Price from tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate manufacturers

Nanjing Fred Technology Co., Ltd
Product
Tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 571188-59-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-28
Sinoway Industrial co., ltd.
Product
Palbociclib side chain 571188-59-5
Price
US $0.00-0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
0.98
Supply Ability
20 tons
Release date
2023-05-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 571188-59-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-30

571188-59-5, tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylateRelated Search:


  • 1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE
  • OTAVA-BB 1207229
  • 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
  • 1-Piperazinecarboxylic acid, 4-(6-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
  • tert-butyl 4-(6-aMinopyri
  • 4-(6-aMinopyridin-3-yl)piperazine-1-carboxylic
  • PALBOCICLIB4
  • 2-Methyl-2-propanyl 4-(6-amino-3-pyridinyl)-1-piperazinecarboxylate
  • 6-(6-Aminopyridin-3-yl)piperazine, N1-BOC protected 98%
  • 1-Butyloxycarbonyl-4-(6-aminopyridin-3-yl)-piperazine
  • Palbociclib Impurity 68
  • Palbociclib-018
  • Palbociclib-11
  • Tert-buty 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
  • POB02
  • OTAVA-BB 1207229/1-Boc-4-(6-aminopyridin-3-yl)piperazine
  • tert-butyl 4-(6-aminoyridin-3-yl)pipera-zine-1-carboxylate
  • 4-(6-AMinopyridin-3-yl)-1-Boc-piperazine
  • tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
  • tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate(For Palbociclib)
  • Palbociclib's intermediate
  • 4-(6-aMinopyridin-3-yl)p
  • t-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)
  • Palbociclib Intermediate
  • Ribociclib-2
  • <i>tert</i>-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate
  • Tert-Butyl 4-(6-Amino-3-Pyrimidin)Piperazine-1-Carboxylate
  • 4-(6-Amino-3-pyridyl)piperazine-1-carboxylic Acid tert-Butyl Ester
  • OTAVA-BB 1207229 tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • 1-(tert-Butoxycarbonyl)-4-(6-aminopyridin-3-yl)piperazine
  • OTAVA-BB
  • Palbociclib Intermediate 1, tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • OTAVA-BB 1207229/1-Boc-4-(6-aminopyridin-3-yl)piperazine(571188-59-5)
  • 4-(6-Amino-3-pyridyl)-1-Boc-piperazine
  • 1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZIN
  • tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate &gt
  • 4-(6-aminopyridine-3-yl) piperazine-1-carboxylic tert-butyl ester
  • )piperazine-1-carboxyL
  • Ribociclib Related Compound 1
  • Tert-Butyl 4-(6-aminopyridin-3-piperazine-1-carboxylate
  • 4-(6- aminopyridine -3- yl) piperazine -1- tert-butyl carboxylate
  • ert-Butyl4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • 1-Boc-4-(6-amino-3-pyridyl)piperazine
  • 1-tert-Butoxycarbonyl-4-(6-amino-3-pyridyl)piperazine
  • tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
  • Palbociclib side chain
  • 4- (6-aminopyridine-3-yl) piperazin-1-carboxylic acid tert-butyl ester
  • tert-Butyl-4-(6-aminopyridin-3-yl)piperazin-1-carboxylate
  • 571188-59-5
  • 571188-59-9
  • PD 0332991
  • Palbociclib
  • Anticancer
  • 571188-59-5