1-N-BOC-4-BROMOPIPERIDINE

Product Name: 1-N-BOC-4-BROMOPIPERIDINE
CAS No.: 180695-79-8
Chemical Name: 1-N-BOC-4-BROMOPIPERIDINE
Synonyms: 1-Boc-4-bromopiperidine;1-Boc-4-broMopiperidin;4-BroMo-N-Boc-piperidine;N-BOC-4-BROMO-PIPERIDINE;1-N-BOC-4-BROMOPIPERIDINE;4-Bromo-2,22-diaminopyridine;1-tert-Butoxycarbonyl-4-bromopiperidine;ert-butyl4-bromopiperidine-1-carboxylate;tert-Butyl 4-bromo-1-piperidinecarboxylate;tert-Butyl 4-bromopiperidine-1-carboxylate
CBNumber: CB1127607
Molecular Formula: C10H18BrNO2
Formula Weight: 264.16
MOL File: 180695-79-8.mol

More

Less

1-N-BOC-4-BROMOPIPERIDINE Property

Melting point:: 42 °C
Boiling point:: 100-118 °C/0.5 mmHg
Density: 1.3403 g/mL at 25 °C
refractive index: n20/D 1.4905
Flash point:: 110 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to lump
pka: -2.77±0.40(Predicted)
color: White to Light yellow
InChI: InChI=1S/C10H18BrNO2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7H2,1-3H3
InChIKey: KZBWIYHDNQHMET-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(Br)CC1
CAS DataBase Reference: 180695-79-8

More

Less

Safety

Hazard Codes: Xn,N
Risk Statements: 22-50
Safety Statements: 61
RIDADR: UN 3082 9/PG 3
WGK Germany: 3
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 687448
Product name: 1-Boc-4-bromopiperidine
Purity: 97%
Packaging: 5g
Price: $95.64
Updated: 2025/07/31

TCI Chemical

Product number: B5585
Product name: 1-tert-Butoxycarbonyl-4-bromopiperidine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $46
Updated: 2025/07/31

TCI Chemical

Product number: B5585
Product name: 1-tert-Butoxycarbonyl-4-bromopiperidine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $183
Updated: 2025/07/31

TRC

Product number: B695110
Product name: tert-Butyl4-Bromopiperidine-1-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB11171
Product name: 1-N-Boc-4-bromopiperidine
Packaging: 5G
Price: $60
Updated: 2021/12/16

More

Less

1-N-BOC-4-BROMOPIPERIDINE Chemical Properties,Usage,Production

Uses

N-Boc-4-Bromopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

24424-99-5

54288-70-9

180695-79-8

Step 1: Synthesis of tert-butyl 4-bromopiperidine-1-carboxylate To a 35 mL dichloromethane suspension containing 5 g (0.02 mol) of 4-bromopiperidine hydrobromide, 7.09 mL (0.04 mol) of N,N-diisopropylethylamine was added slowly and dropwise at 0 °C. The reaction mixture was stirred for 30 minutes and then continued with the dropwise addition of 6.67 g (0.031 mol) of di-tert-butyl dicarbonate to a 35 mL dichloromethane solution. The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the reaction mixture was washed sequentially with 1 M aqueous hydrochloric acid (2 x 30 mL) and brine (30 mL). The organic layer was separated, dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated under reduced pressure to give 6.9 g of 4-bromopiperidine-1-carboxylic acid tert-butyl ester as a yellow oil in quantitative yield. The product was characterized by 1H NMR (250 MHz, chloroform-d): δ 1.46 (9H, s), 1.79-2.00 (2H, m), 2.00-2.16 (2H, m), 3.31 (2H, ddd, J = 13.67,7.73,3.73 Hz), 3.68 (2H, ddd, J = 13.55,6.85,3.65 Hz), 4.34 (1H, tt, J = 7.69,3.81 Hz).

References

[1] Patent: US2010/76029, 2010, A1. Location in patent: Page/Page column 42
[2] Patent: US2011/71196, 2011, A1. Location in patent: Page/Page column 22; 23
[3] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 311 - 321
[4] Journal of the American Chemical Society, 2016, vol. 138, # 24, p. 7520 - 7523
[5] Organic Letters, 2000, vol. 2, # 1, p. 6 - 10

1-N-BOC-4-BROMOPIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-N-BOC-4-BROMOPIPERIDINE Suppliers

Americas 1 China 162 Europe 1 India 3 Japan 1 Switzerland 1 United Kingdom 3 United States 21 Global 193

Jiaxing Rich Biological Technology Co., Ltd.

Tel: 0573-11111111-1111 18969316891
Fax: -
Email: richmol@163.com
Country: China
ProdList: 449
Advantage: 50

Changzhou Xiya Biotechnology Co., Ltd.

Tel: 13775267187
Email: 391097727@qq.com
Country: China
ProdList: 996
Advantage: 58

Shanghai Hobor Chemical Co., Ltd

Tel: 021-57790084; 13918007836
Fax: 021-51685238
Email: sales@hoborchem.com
Country: China
ProdList: 392
Advantage: 60

BTC Pharmaceutical CO. Ltd

Tel: 15716293042 18862996710
Fax: 0513-68015394
Email: 15050603958@163.com
Country: China
ProdList: 694
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

More

Less

View Lastest Price from 1-N-BOC-4-BROMOPIPERIDINE manufacturers

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

Product: 1-Boc-4-bromopiperidine 180695-79-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5ton/month
Release date: 2023-12-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Boc-4-bromopiperidine 180695-79-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 1-N-BOC-4-BROMOPIPERIDINE 180695-79-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 500kg
Release date: 2018-08-17

180695-79-8, 1-N-BOC-4-BROMOPIPERIDINERelated Search:

Tetramethrin Butyl benzoate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Formic acid 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 4-Bromomethypiperidine-1-carboxylic acid tert-butyl ester 1-Boc-4-methanesulfonyloxypiperidine 1-Boc-4-methylpiperidine-4-carboxylic acid tert-Butyl 4-iodopyrazole-1-carboxylate 1-Boc-pyrazole-4-boronic acid pinacol ester N-BOC-piperidine-4-carboxylic acid N-Boc-piperidine-4-aldehyde tert-Butyl 3-bromopropylcarbamate 1-N-BOC-4-BROMOPIPERIDINE 1-N-BOC-3-BROMOPIPERIDINE,1-Boc-3-bromopiperidine 4-BROMO-N-METHYL PIPERIDINE N-Boc-trans-4-bromo-3-hydroxypipiridine

1-N-BOC-4-BROMOPIPERIDINE

N-BOC-4-BROMO-PIPERIDINE

1-Piperidinecarboxylic acid, 4-bromo-, 1,1-dimethylethyl ester

1-Boc-4-bromopiperidine

tert-Butyl 4-bromopiperidine-1-carboxylate

1-Boc-4-broMopiperidin

4-BroMo-N-Boc-piperidine

1-tert-Butoxycarbonyl-4-bromopiperidine

tert-butyl 3-allyl-3-hydroxyazetidine-94-carboxylate

4-Bromo-2,22-diaminopyridine

1,1-Dimethylethyl 4-bromo-1-piperidinecarboxylate

ert-butyl4-bromopiperidine-1-carboxylate

tert-Butyl 4-bromo-1-piperidinecarboxylate

180695-79-8

pharmacetical

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Piperidines

PiperidinesHeterocyclic Building Blocks