ChemicalBook > CAS DataBase List > phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate
- Product Name
- phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate
- CAS No.
- 417722-95-3
- Chemical Name
- phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate
- Synonyms
- Lenvatinib Impurity 58;LenvatinibImpurity12HCl;Lenvatinib Intermediates 2;Phenyloxy Descyclopropylamino Lenvatinib;Phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2-chlorophenyl)carbamate;phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate;Phenyl N-[4-[[6-(aminocarbonyl)-7-methoxy-4-quinolinyl]oxy]-2-chlorophenyl]carbamate;Carbamic acid,[4-[[6-(aminocarbonyl)-7-methoxy-4-quinolinyl]oxy]-2-chlorophenyl]-,phenyl ester;CARBAMIC ACID,[4-[[6-(AMINOCARBONYL)-7-METHOXY-4-QUINOLINYL]OXY]-2-CHLOROPHENYL]-,PHENYL ESTER;;Carbamic acid, N-[4-[[6-(aminocarbonyl)-7-methoxy-4-quinolinyl]oxy]-2-chlorophenyl]-, phenyl ester
- CBNumber
- CB33147460
- Molecular Formula
- C24H18ClN3O5
- Formula Weight
- 463.87
- MOL File
- 417722-95-3.mol
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phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Property
- Boiling point:
- 644.8±55.0 °C(Predicted)
- Density
- 1.418±0.06 g/cm3(Predicted)
- pka
- 11.16±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H319Causes serious eye irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
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phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Chemical Properties,Usage,Production
Uses
Phenyloxy Descyclopropylamino Lenvatinib is an intermediate in the synthesis of Descyclopropyl Lenvatinib (D288150), a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
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417722-95-3, phenyl (4-((6-carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)carbamateRelated Search:
Lenvatinib Impurity P
1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea
Lenvatinib Impurity 8
Lenvatinib Impurity f
6-Quinolinecarboxylic acid, 4-(4-amino-3-chlorophenoxy)-7-methoxy-, methyl ester
Lenvatinib Impurity 5
Lenvatinib Impurity O
6-Quinolinecarboxamide, 4-[3-chloro-4-[[(ethylamino)carbonyl]amino]phenoxy]-7-methoxy-
6-Quinolinecarboxamide, 4-[(2-chloro-4-hydroxyphenyl)amino]-7-methoxy-
6-Quinolinecarboxamide, 4-hydroxy-7-methoxy-
Descyclopropyl Lenvatinib
4-(4-amino-3-chlorophenoxy)-7-methoxyquinoline-6-carboxamide
4,4'-[Carbonylbis[imino(3-chloro-4,1-phenylene)oxy]]bis[7-methoxy-6-quinolinecarboxamide]
Lenvatinib Impurity 2
Lenvatinib Impurity d
7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxaMide
4-chloro-7-Methoxyquinoline-6-carboxaMide
Lenvatinib Impurity 12