CRANAD 28

Product Name: CRANAD 28
CAS No.: 1623747-97-6
Chemical Name: CRANAD 28
Synonyms: CRANAD 28;CRANAD-28,beta plaques,Inhibitor,CRANAD 28,inhibit;1,7-Bis(5-methyl-1-phenyl-1H-pyrazol-4-yl)hepta-1,6-diene-3,5-dione-difluoroboron;4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(5-methyl-1-phenyl-1H-pyrazole);4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(5-methyl-1-phenyl-1H-pyrazole);4-[(E)-2-[2,2-difluoro-6-[2-(5-methyl-1-phenylpyrazol-1-ium-4-ylidene)ethylidene]-1,3-dioxa-2-boranuidacyclohex-4-en-4-yl]ethenyl]-5-methyl-1-phenylpyrazole
CBNumber: CB33152594
Molecular Formula: C27H23BF2N4O2
Formula Weight: 484.3049264
MOL File: 1623747-97-6.mol

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CRANAD 28 Property

storage temp.: Store at -20°C
solubility: DMF: 2 mg/ml; DMSO: 2 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
color: Orange to red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19816
Product name: CRANAD 28
Purity: ≥98%
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 19816
Product name: CRANAD 28
Purity: ≥98%
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 19816
Product name: CRANAD 28
Purity: ≥98%
Packaging: 5mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 19816
Product name: CRANAD 28
Purity: ≥98%
Packaging: 10mg
Price: $426
Updated: 2024/03/01

AK Scientific

Product number: SYN5491
Product name: CRANAD-28
Packaging: 50mg
Price: $1268
Updated: 2021/12/16

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CRANAD 28 Chemical Properties,Usage,Production

Description

CRANAD 28 is a curcumin derivative and non-conjugated fluorescent affinity probe for the detection of amyloid-β (Aβ) in vitro and in vivo that has excitation/emission spectra of 498/578 nm, respectively. It binds to various forms of Aβ, including Aβ40 monomers and aggregates, as well as Aβ42 monomers, dimers, and oligomers (K_ds = 68.8, 52.4, 159.7, 162.9, and 85.7 nM, respectively). When bound to Aβ, the fluorescence intensity decreases, in contrast to similar curcumin-based fluorescent probes. CRANAD 28 labels amyloid plaques and cerebral amyloid angiopathy both in APP/PS1 mouse brain sections and in live mice following i.v. administration. It also inhibits copper-induced and naturally occurring Aβ crosslinking.

CRANAD 28 Preparation Products And Raw materials

Raw materials

Preparation Products

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CRANAD 28 Suppliers

China 35 United States 4 Global 39

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

Tel: 024-024-88590548 18341751992
Email: 757984502@qq.com
Country: China
ProdList: 891
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7850
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
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DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
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Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3600
Advantage: 58

1623747-97-6, CRANAD 28Related Search:

4-[(E)-2-[2,2-difluoro-6-[2-(5-methyl-1-phenylpyrazol-1-ium-4-ylidene)ethylidene]-1,3-dioxa-2-boranuidacyclohex-4-en-4-yl]ethenyl]-5-methyl-1-phenylpyrazole

CRANAD 28

1,7-Bis(5-methyl-1-phenyl-1H-pyrazol-4-yl)hepta-1,6-diene-3,5-dione-difluoroboron

4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(5-methyl-1-phenyl-1H-pyrazole)

CRANAD-28,beta plaques,Inhibitor,CRANAD 28,inhibit

4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(5-methyl-1-phenyl-1H-pyrazole)

1623747-97-6

C27H23BF2N4O2