ChemicalBook > CAS DataBase List > GLPG0187

GLPG0187

Product Name
GLPG0187
CAS No.
1320346-97-1
Chemical Name
GLPG0187
Synonyms
CS-2550;GLPG0187;GLPG 0187;GLPG-0187;GLPG0187, 10 mM in DMSO;inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin;GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity;L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-;(S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid;(2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid
CBNumber
CB33159669
Molecular Formula
C29H37N7O5S
Formula Weight
595.71
MOL File
1320346-97-1.mol
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GLPG0187 Property

Boiling point:
894.7±75.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:8.0(Max Conc. mg/mL);13.43(Max Conc. mM)
form 
A crystalline solid
pka
2.86±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21792
Product name
GLPG0187
Purity
≥98%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
21792
Product name
GLPG0187
Purity
≥98%
Packaging
5mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
21792
Product name
GLPG0187
Purity
≥98%
Packaging
10mg
Price
$286
Updated
2024/03/01
Tocris
Product number
7059
Product name
GLPG0187
Purity
≥97%(HPLC)
Packaging
10
Price
$215
Updated
2021/12/16
TRC
Product number
G411800
Product name
GLPG-0187
Packaging
5mg
Price
$330
Updated
2021/12/16
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GLPG0187 Chemical Properties,Usage,Production

Uses

GLPG-0187 is an integrin receptor antagonist which displays anti-tumor activity.

in vivo

Blocking αv-integrins by GLPG0187 markedly reduces their metastatic tumor growth. Bone tumor burden is significantly lower and the number of bone metastases/mouse is significantly inhibited. The progression of bone metastases and the formation of new bone metastases during the treatment period is significantly inhibited[1].

storage

Store at -20°C

GLPG0187 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLPG0187 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003;025-846993838003-8003 18013301593;18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3293
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3505
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4817
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9505
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
9955
Advantage
58

1320346-97-1, GLPG0187Related Search:


  • GLPG0187
  • GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity
  • (S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid
  • CS-2550
  • GLPG 0187;GLPG-0187
  • L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-
  • inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin
  • (2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid
  • GLPG0187, 10 mM in DMSO
  • 1320346-97-1