ChemicalBook > CAS DataBase List > GLPG0187
GLPG0187
- Product Name
- GLPG0187
- CAS No.
- 1320346-97-1
- Chemical Name
- GLPG0187
- Synonyms
- CS-2550;GLPG0187;GLPG 0187;GLPG-0187;GLPG0187, 10 mM in DMSO;inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin;GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity;L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-;(S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid;(2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid
- CBNumber
- CB33159669
- Molecular Formula
- C29H37N7O5S
- Formula Weight
- 595.71
- MOL File
- 1320346-97-1.mol
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GLPG0187 Property
- Boiling point:
- 894.7±75.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:8.0(Max Conc. mg/mL);13.43(Max Conc. mM)
- form
- A crystalline solid
- pka
- 2.86±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21792
- Product name
- GLPG0187
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $49
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21792
- Product name
- GLPG0187
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $190
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21792
- Product name
- GLPG0187
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $286
- Updated
- 2024/03/01
Tocris
- Product number
- 7059
- Product name
- GLPG0187
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $215
- Updated
- 2021/12/16
TRC
- Product number
- G411800
- Product name
- GLPG-0187
- Packaging
- 5mg
- Price
- $330
- Updated
- 2021/12/16
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GLPG0187 Chemical Properties,Usage,Production
Uses
GLPG-0187 is an integrin receptor antagonist which displays anti-tumor activity.
in vivo
Blocking αv-integrins by GLPG0187 markedly reduces their metastatic tumor growth. Bone tumor burden is significantly lower and the number of bone metastases/mouse is significantly inhibited. The progression of bone metastases and the formation of new bone metastases during the treatment period is significantly inhibited[1].
storage
Store at -20°C
GLPG0187 Preparation Products And Raw materials
Raw materials
Preparation Products
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GLPG0187 Suppliers
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