Azido-PEG3-S-PEG4-propargyl

Product Name: Azido-PEG3-S-PEG4-propargyl
CAS No.: 2055041-24-0
Chemical Name: Azido-PEG3-S-PEG4-propargyl
Synonyms: Azido-PEG3-S-PEG4-propargyl
CBNumber: CB33162870
Molecular Formula: C19H35N3O7S
Formula Weight: 449.56
MOL File: 2055041-24-0.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23193
Product name: Azido-PEG3-S-PEG4-propargyl
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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Azido-PEG3-S-PEG4-propargyl Chemical Properties,Usage,Production

Description

Azido-PEG3-S-PEG4-propargyl is a crosslinker containing a propargyl group and an azide group. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The azide group enables PEGylation via Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Azido-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG3-S-PEG4-propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG3-S-PEG4-propargyl Suppliers

China 13 United States 2 Global 15

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

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View Lastest Price from Azido-PEG3-S-PEG4-propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG3-S-PEG4-propargyl 2055041-24-0
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2055041-24-0, Azido-PEG3-S-PEG4-propargylRelated Search:

Azido-PEG3-Val-Cit-PAB-PNP Azido-PEG3-S-PEG4-t-butyl ester Azdo-PEG3-S-PEG3-Azide Azido-PEG4-NHBoc Azido-PEG3-Val-Cit-PAB-OH

Azido-PEG3-S-PEG4-propargyl

2055041-24-0