ChemicalBook > CAS DataBase List > Memogain
Memogain
- Product Name
- Memogain
- CAS No.
- 224169-27-1
- Chemical Name
- Memogain
- Synonyms
- GLN-1062;Memogain;GLN-1062 ，E2227;GLN-1062, 10 mM in DMSO;Benzgalantamine (GLN-1062);Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062;(4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate;Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6;6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-;Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
- CBNumber
- CB33175551
- Molecular Formula
- C24H25NO4
- Formula Weight
- 391.46
- MOL File
- 224169-27-1.mol
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Memogain Property
- Boiling point:
- 523.2±50.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 7.78±0.40(Predicted)
- form
- Solid
- color
- White to yellow
- InChI
- InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
- InChIKey
- JKVNJTYHRABHIY-WXVUKLJWSA-N
- SMILES
- N1(C)CC2=CC=C(OC)C3O[C@]4([H])[C@@](C=C[C@H](OC(=O)C5=CC=CC=C5)C4)(C2=3)CC1
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Memogain Chemical Properties,Usage,Production
Uses
Galantamine Benzoate-D3 is an isotopic labelled compound of Galantamine Benzoate, a pro-drug that slows down plaque deposition and ameliorates behavior in 5X familial Alzheimer's disease mice.
in vivo
Benzgalantamine (Memogain, 0.3-3 mg/kg, intranasal, twice a day for 2 weeks) improves cognitive function by promoting neurogenesis in the hippocampus, specifically in the dentate gyrus and CA1 regions of the hippocampus in rats models[2].
| Animal Model: | Sprague Dawley rats models[2] |
| Dosage: | 0.3-3 mg/kg |
| Administration: | intranasal, twice a day for 2 weeks |
| Result: | Increased the number of newly generated cells and immunolabeling of synaptic markers in the dentate gyrus and CA1 regions of the hippocampus. |
Memogain Preparation Products And Raw materials
Raw materials
Preparation Products
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