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Memogain

Product Name
Memogain
CAS No.
224169-27-1
Chemical Name
Memogain
Synonyms
GLN-1062;Memogain;GLN-1062 ,E2227;GLN-1062, 10 mM in DMSO;Benzgalantamine (GLN-1062);Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062;(4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate;Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6;6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-;Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
CBNumber
CB33175551
Molecular Formula
C24H25NO4
Formula Weight
391.46
MOL File
224169-27-1.mol
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Memogain Property

Boiling point:
523.2±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
7.78±0.40(Predicted)
form 
Solid
color 
White to yellow
InChI
InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
InChIKey
JKVNJTYHRABHIY-WXVUKLJWSA-N
SMILES
N1(C)CC2=CC=C(OC)C3O[C@]4([H])[C@@](C=C[C@H](OC(=O)C5=CC=CC=C5)C4)(C2=3)CC1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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Memogain Chemical Properties,Usage,Production

Uses

Galantamine Benzoate-D3 is an isotopic labelled compound of Galantamine Benzoate, a pro-drug that slows down plaque deposition and ameliorates behavior in 5X familial Alzheimer's disease mice.

in vivo

Benzgalantamine (Memogain, 0.3-3 mg/kg, intranasal, twice a day for 2 weeks) improves cognitive function by promoting neurogenesis in the hippocampus, specifically in the dentate gyrus and CA1 regions of the hippocampus in rats models[2].

Animal Model:Sprague Dawley rats models[2]
Dosage:0.3-3 mg/kg
Administration:intranasal, twice a day for 2 weeks
Result:Increased the number of newly generated cells and immunolabeling of synaptic markers in the dentate gyrus and CA1 regions of the hippocampus.

Memogain Preparation Products And Raw materials

Raw materials

Preparation Products

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Memogain Suppliers

Vinsce Bio pharm (Suzhou) Co Ltd
Tel
13775593029
Email
sales@vinsce.com
Country
China
ProdList
45
Advantage
58
Jiangshan Chuangsheng Bioengineering Co., Ltd
Tel
13775204409 13775204409
Email
164866523@qq.com
Country
China
ProdList
208
Advantage
58
XianTao Li Zhao
Tel
18571672902
Email
1010771219@qq.com
Country
China
ProdList
362
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
9955
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
4899
Advantage
58

224169-27-1, MemogainRelated Search:


  • Memogain
  • GLN-1062
  • 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-
  • Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6
  • Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
  • Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062
  • (4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate
  • GLN-1062, 10 mM in DMSO
  • Benzgalantamine (GLN-1062)
  • GLN-1062 ,E2227
  • 224169-27-1