ChemicalBook > CAS DataBase List > Memogain

Memogain

Product Name
Memogain
CAS No.
224169-27-1
Chemical Name
Memogain
Synonyms
GLN-1062;Memogain;GLN-1062 ,E2227;GLN-1062, 10 mM in DMSO;Benzgalantamine (GLN-1062);Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062;(4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate;Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6;6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-;Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
CBNumber
CB33175551
Molecular Formula
C24H25NO4
Formula Weight
391.46
MOL File
224169-27-1.mol
More
Less

Memogain Property

Boiling point:
523.2±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
7.78±0.40(Predicted)
form 
Solid
color 
White to yellow
InChI
InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
InChIKey
JKVNJTYHRABHIY-WXVUKLJWSA-N
SMILES
N1(C)CC2=CC=C(OC)C3O[C@]4([H])[C@@](C=C[C@H](OC(=O)C5=CC=CC=C5)C4)(C2=3)CC1
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

Memogain Chemical Properties,Usage,Production

Uses

Galantamine Benzoate-D3 is an isotopic labelled compound of Galantamine Benzoate, a pro-drug that slows down plaque deposition and ameliorates behavior in 5X familial Alzheimer's disease mice.

in vivo

Benzgalantamine (Memogain, 0.3-3 mg/kg, intranasal, twice a day for 2 weeks) improves cognitive function by promoting neurogenesis in the hippocampus, specifically in the dentate gyrus and CA1 regions of the hippocampus in rats models[2].

Animal Model:Sprague Dawley rats models[2]
Dosage:0.3-3 mg/kg
Administration:intranasal, twice a day for 2 weeks
Result:Increased the number of newly generated cells and immunolabeling of synaptic markers in the dentate gyrus and CA1 regions of the hippocampus.

Memogain Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Memogain Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

224169-27-1, MemogainRelated Search:


  • Memogain
  • GLN-1062
  • 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-
  • Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6
  • Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
  • Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062
  • (4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate
  • GLN-1062, 10 mM in DMSO
  • Benzgalantamine (GLN-1062)
  • GLN-1062 ,E2227
  • 224169-27-1