ChemicalBook > CAS DataBase List > Quinoline-5-carboxaldehyde

Quinoline-5-carboxaldehyde

Product Name: Quinoline-5-carboxaldehyde
CAS No.: 22934-41-4
Chemical Name: Quinoline-5-carboxaldehyde
Synonyms: 5-Formylquinoline;AKOS BBS-00005336;CHEMBRDG-BB 4300479;RARECHEM AK ML 0025;5-Quinolinecarbaldehyde;QUINOLINE-5-CARBALDEHYDE;5-QUINOLINECARBOXALDEHYDE;QUINOLINE-5-CARBOXALDEHYDE;Quinoline-5-carbaldehyde(QUC);Quinoline-5-carboxaldehyde, 97+%
CBNumber: CB3323737
Molecular Formula: C10H7NO
Formula Weight: 157.17
MOL File: 22934-41-4.mol

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Quinoline-5-carboxaldehyde Property

Melting point:: 95-96°C
Boiling point:: 314.3±15.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 3.94±0.12(Predicted)
Appearance: Yellow to brown Solid
Water Solubility: Slightly soluble in water.
Sensitive: Air Sensitive
BRN: 113095
CAS DataBase Reference: 22934-41-4(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38-43
Safety Statements: 26-36/37/39-36/37
HazardClass: IRRITANT
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: Q990025
Product name: Quinoline-5-carbaldehyde
Packaging: 100mg
Price: $75
Updated: 2021/12/16

BroadPharm

Product number: BP-20325
Product name: QUINOLINE-5-CARBALDEHYDE
Purity: 97%
Packaging: 1g
Price: $186
Updated: 2021/12/16

Matrix Scientific

Product number: 054396
Product name: Quinoline-5-carbaldehyde
Packaging: 500mg
Price: $205
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0999338
Product name: 5-FORMYLQUINOLINE
Purity: 95.00%
Packaging: 5MG
Price: $498.94
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H15-1-30
Product name: Quinoline-5-carboxaldehyde
Packaging: 5G
Price: $568
Updated: 2021/12/16

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Quinoline-5-carboxaldehyde Chemical Properties,Usage,Production

Uses

Quinoline-5-carboxaldehyde is used as a precursor in the preparation of pharmaceuticals.

Synthesis

4964-71-0

68-12-2

22934-41-4

General method: n-Butyllithium (2.5 M hexane solution, 300 μL, 0.72 mmol) was added slowly and dropwise to a solution of anhydrous THF (1.5 mL) of 5-bromoquinoline (100 mg, 0.48 mmol) at -78°C. The reaction solution turned red immediately. The reaction solution immediately turned red, followed by the addition of N,N-dimethylformamide (192 μL, 2.49 mmol). After maintaining the reaction temperature at -78 °C with stirring for 10 min, the reaction was quenched with deionized water (6 mL). The reaction mixture was poured into saturated aqueous sodium bicarbonate solution (10 mL) and extracted with ethyl acetate (3 × 10 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: n-hexane solution of 10% ethyl acetate) to give 5-quinolinecarboxaldehyde as a yellow solid in 53% yield.

References

[1] European Journal of Medicinal Chemistry, 2019, p. 290 - 320

Quinoline-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Quinoline-5-carboxaldehyde manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Quinoline-5-carboxaldehyde 22934-41-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-23

Career Henan Chemical Co

Product: Quinoline-5-carboxaldehyde 22934-41-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

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Quinoline-5-carboxaldehyde ISO 9001：2015 REACH

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22934-41-4

ALDEHYDE

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