Quinoline-5-carboxylic acid
- Product Name
- Quinoline-5-carboxylic acid
- CAS No.
- 7250-53-5
- Chemical Name
- Quinoline-5-carboxylic acid
- Synonyms
- NSC30045;AKOS BBS-00005337;5-quinolinic acid;RARECHEM AL BE 1510;Quinoline-5-carboxylic;Quinoline-5-carboxylicaci;5-quinolinecarboxylic acid;QUINOLINE-5-CARBOXYLIC ACID;5-Quinolinecarboxylic Acid >Quinoline-5-carboxylicacid,98+%
- CBNumber
- CB9730777
- Molecular Formula
- C10H7NO2
- Formula Weight
- 173.17
- MOL File
- 7250-53-5.mol
Quinoline-5-carboxylic acid Property
- Melting point:
- >300°C
- Boiling point:
- 386.5±15.0 °C(Predicted)
- Density
- 1.339±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 0.97±0.10(Predicted)
- color
- White to Gray to Red
- Water Solubility
- Slightly soluble in water.
- BRN
- 129178
- InChI
- InChI=1S/C10H7NO2/c12-10(13)8-3-1-5-9-7(8)4-2-6-11-9/h1-6H,(H,12,13)
- InChIKey
- RAYMXZBXQCGRGX-UHFFFAOYSA-N
- SMILES
- N1C2C(=C(C(O)=O)C=CC=2)C=CC=1
- CAS DataBase Reference
- 7250-53-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-36/38-22
- Safety Statements
- 26-36-37/39-37
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29334900
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS001076
- Product name
- 5-Quinolinecarboxylic acid
- Purity
- AldrichCPR
- Packaging
- 1g
- Price
- $230
- Updated
- 2026/03/19
- Product number
- Q0089
- Product name
- 5-Quinolinecarboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $111
- Updated
- 2026/03/19
- Product number
- Q990018
- Product name
- Quinoline-5-carboxylicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- JK392108
- Product name
- Quinoline-5-carboxylicacid
- Purity
- 95%
- Packaging
- 250mg
- Price
- $62
- Updated
- 2021/12/16
- Product number
- 012039
- Product name
- Quinoline-5-carboxylic acid
- Packaging
- 500mg
- Price
- $23
- Updated
- 2021/12/16
Quinoline-5-carboxylic acid Chemical Properties,Usage,Production
Uses
Quinoline-5-carboxylic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.
Application
Quinoline-5-carboxylic acid could synthesize a thermally stable microporous metal-organic framework (MOF Ni-Qc-5) to enhance the separation of CH4 against N2. The highest adsorption CH4 uptake (1.3 mmol/g) was achieved compared to N2 (0.28 mmol/g). Compared with other MOF materials, Ni-Qc-5 possessed very low adsorption energy and high selectivity at low pressure of 0.1 bar[1].
Synthesis
Synthesis of methyl quinoline-5-carboxylate (Intermediate-97):
A 500 mL RB flask equipped with a magnetic stirrer was charged with m-aminobenzoic acid (60 g, 435 mmol), glycerol (168 g, 1824 mmol) in 90 mL of concentrated H25O4. RB flask equipped with a magnetic stirrer was charged with m-aminobenzoic acid (60 g, 435 mmol), glycerol (168 g, 1824 mmol), 3-nitrobenzoic acid (30 g, 179 mmol) in 90 mL of concentrated H25O4. The reaction mixture was heated at 150 C for 7 h. After the reaction was cooled to room temperature MeOH (600 mL) was added and refluxed for 12 hours. It was then cooled to 0C, burst with ice and concentrated. The crude reaction mixture was alkalized with NaHCO3, extracted with DCM and concentrated. The resulting crude material was purified by silica gel column chromatography using petroleum ether (60-80), ethyl acetate and 0.5% triethylamine as eluents. A product (Intermediate-97) was obtained as a brown liquid (21 g).
Synthesis of quinoline-5-carboxylic acid (Intermediate-98):
To a stirred solution of Intermediate-97 (21 g, 112 mmol) in THF:MeOH mixture (25 mL:200 mL) at 0 C, LiOH (10.75 g, 448 mmol) in water (25 mL) was added. The resulting reaction mixture was stirred at room temperature for 3 hours. After the reaction (monitored by TLC), it was concentrated and acidified with 1N.HCl (pH = 5). The resulting precipitate was filtered and dried to yield intermediate-98 (19 g).
References
[1] Salman Qadir. “A thermally stable isoquinoline based ultra-microporous metal-organic framework for CH4 separation from coal mine methane.” Chemical Engineering Journal 51 1 (1900): 131136.
Quinoline-5-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Quinoline-5-carboxylic acid manufacturers
- Product
- Quinoline-5-carboxylic acid 7250-53-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-23
- Product
- Quinoline-5-carboxylic acid 7250-53-5
- Price
- US $950.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-03-19
- Product
- Quinoline-5-carboxylic acid 7250-53-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10