3-Quinolinecarboxylic acid
- Product Name
- 3-Quinolinecarboxylic acid
- CAS No.
- 6480-68-8
- Chemical Name
- 3-Quinolinecarboxylic acid
- Synonyms
- QUINOLINE-3-CARBOXYLIC ACID;AKOS BBS-00005333;3-Carboxyquinoline.;RARECHEM AL BO 1256;3-QUINOLINECARBOXYLIC ACID;3-Quinolinecarboxylic acid 98%;3-Quinolinecarboxylic acid,98%;3-Quinolinecarboxylic Acid >Quinoline-3-carboxylic acid 97%;Quinoline-3-carboxylic acid ,98%
- CBNumber
- CB5308619
- Molecular Formula
- C10H7NO2
- Formula Weight
- 173.17
- MOL File
- 6480-68-8.mol
3-Quinolinecarboxylic acid Property
- Melting point:
- 277-280 °C (lit.)
- Boiling point:
- 303.81°C (rough estimate)
- Density
- 1.2427 (rough estimate)
- refractive index
- 1.5200 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Powder
- pka
- 2.20±0.30(Predicted)
- color
- White to slightly beige
- BRN
- 126542
- InChI
- InChI=1S/C10H7NO2/c12-10(13)8-5-7-3-1-2-4-9(7)11-6-8/h1-6H,(H,12,13)
- InChIKey
- DJXNJVFEFSWHLY-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC=CC=2)C=C(C(O)=O)C=1
- CAS DataBase Reference
- 6480-68-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36/38
- Safety Statements
- 22-24/25-37/39-26-37
- WGK Germany
- 3
- HS Code
- 29334900
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 177148
- Product name
- 3-Quinolinecarboxylic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $40.9
- Updated
- 2026/03/19
- Product number
- 177148
- Product name
- 3-Quinolinecarboxylic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $118
- Updated
- 2026/03/19
- Product number
- Q0090
- Product name
- 3-Quinolinecarboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $29
- Updated
- 2026/03/19
- Product number
- Q0090
- Product name
- 3-Quinolinecarboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $98
- Updated
- 2026/03/19
- Product number
- 177148
- Product name
- 3-Quinolinecarboxylic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $219
- Updated
- 2026/03/19
3-Quinolinecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
WHITE TO SLIGHTLY BEIGE POWDER
Uses
A quinoline derivative with antimicrobial activity.
General Description
The antibacterial activity of 3-quinolinecarboxylic acid derivatives were evaluated.
Synthesis
In a Schlenk (50 mL) reaction flask with a carbon dioxide balloon attached at the stub, Cu(OAc)2.H2O (0.0125 mmol), 1,2-bis(diphenylphosphino)benzene (0.018 mmol), and 1,4-dioxane (2.0 mL) were added with stirring, and then the flask was placed at 60 C oil bath for 25 min under carbon dioxide atmosphere, followed by the sequential addition of toluene (8 mL), 3-bromoquinoline (1.0 mmol), Pd(OAc)2 (0.03 mmol), 4,5-bis(diphenylphosphino)-9,9-dimethyloxanthene (0.06 mmol), Et3N (2.5 mmol, 2.5 equiva.) and then Carbon dioxide was removed and the reaction was carried out at 100 C until the raw material bromobenzene disappeared, cooled to room temperature and then sodium hydroxide solution (1M, 10.0 mL) was added, stirred for 10 min and then filtered, the solids were washed with water for 3 times, the filtrate was extracted with ethyl acetate (2 x 10 mL) leaving an aqueous layer, the aqueous layer was adjusted to pH 1-2 with hydrochloric acid solution (1 M), extracted with ethyl acetate (3 x 15 mL) and Anhydrous sodium sulfate was dried, and the solvent was removed to obtain quinoline-3-carboxylic acid in 98% yield.
3-Quinolinecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Quinolinecarboxylic acid manufacturers
- Product
- 3-Quinolinecarboxylic acid 6480-68-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- 3-Quinolinecarboxylic acid 6480-68-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-14
- Product
- 3-Quinolinecarboxylic acid 6480-68-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-01-08