ChemicalBook > CAS DataBase List > 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE

Product Name
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
CAS No.
94-19-9
Chemical Name
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
Synonyms
setd;etazol;etazole;globucid;ethazole;globucin;globuzid;sethadil;aethazol;berlophen
CBNumber
CB3325377
Molecular Formula
C10H12N4O2S2
Formula Weight
284.36
MOL File
94-19-9.mol
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4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Property

Melting point:
185.5-186.0°
Density 
1.3410 (rough estimate)
refractive index 
1.6440 (estimate)
pka
pKa 5.36(H2O t = 37) (Uncertain)
Water Solubility 
215mg/L(20 ºC)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
Toxicity
LD50 intraperitoneal in mouse: 1459mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Matrix Scientific
Product number
008104
Product name
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
Packaging
1g
Price
$305
Updated
2021/12/16
AK Scientific
Product number
3860AF
Product name
4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
Packaging
1g
Price
$461
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0165391
Product name
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
Purity
98.00%
Packaging
500MG
Price
$762.3
Updated
2021/12/16
Aronis compounds
Product number
BBC/507
Product name
4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Packaging
10g
Price
$501
Updated
2021/12/16
Aronis compounds
Product number
BBC/507
Product name
4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Packaging
5g
Price
$371
Updated
2021/12/16
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4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Chemical Properties,Usage,Production

Originator

Sul-Spansion,SKF,US,1956

Definition

ChEBI: 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide is a member of benzenes and a sulfonamide.

Manufacturing Process

0.163 mol of 2-amino-5-ethyl-1,3,4-thiadiazole was covered with 43 parts of anhydrous pyridine. To the mixture was added 50 parts (0.214 mol) of pacetylaminobenzenesulfonyl chloride with vigorous shaking at 50°C to 60°C. The reaction mixture was then heated to 125°C. When the mixture had cooled somewhat it was placed in a Claisen flask and 27.6 parts (0.69 mol) of sodium hydroxide dissolved in 110 parts of water was added through a dropping funnel while distilling off a mixture of pyridine and water. The distillation was stopped when the temperature reached 100°C and the residual liquor in the flask heated at 95°C for 30 minutes.The reaction mixture was then poured into 1,650 parts of hot water, the pH adjusted to 8 to 9, decolorizing charcoal was added and the whole was heated on the steam for 15 minutes. The charcoal was filtered off and the hot filtrate neutralized and cooled. The 2-(sulfanilamido)-5-ethyl-1,3,4-thiadiazole was purified by repeated crystallization from boiling water.

Therapeutic Function

Antibacterial

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Suppliers

CARBONE SCIENTIFIC CO.,LTD
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Fluorochem Ltd
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Bio-Farma
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Fluorochem Ltd.
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enquiries@fluorochem.co.uk
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94-19-9, 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDERelated Search:


  • ethazole(pharmaceutical)
  • globucid
  • sulfaethidol
  • sulfaethidole
  • sulfaethylthiadiazole
  • sulfa-perlongit
  • sul-spansion
  • sul-spantab
  • sulphaethidole
  • Sulphanyl acid N-(5-ethyl-1,3,4-thiadiazol-2yl) amide
  • 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
  • ethazole
  • 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide
  • globucin
  • globuzid
  • n-(5-ethyl-1,3,4-thiadiazol-2-yl)-sulfanilamid
  • n-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide
  • setd
  • sethadil
  • sulfaethidiole
  • TIMTEC-BB SBB001155
  • 2-sulfanilamidoaethylthiodiazol
  • 4-amino-n-(5-ethyl-1,3,4-thiadiazol-2-yl)-benzenesulfonamid
  • aethazol
  • berlophen
  • etazol
  • etazole
  • Benzenesulfonamide, 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-
  • 94-19-9
  • C10H12N4O2S2