ChemicalBook > CAS DataBase List > 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Product Name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- CAS No.
- 835616-61-0
- Chemical Name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Synonyms
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione;2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione;Thalidomide 5-fluoride;2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione;135588;Thali-5F;Light purple to off white powder;2-(2,6-dioxo-3-piperidyl)-5-fluoro-isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1,3-isoindolinedione;? 2-(2,6-Dioxopiperidin-3-yl)-5- difluoroisoindoline-1,3-dione
- CBNumber
- CB33266857
- Molecular Formula
- C13H9FN2O4
- Formula Weight
- 276.22
- MOL File
- 835616-61-0.mol
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2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Property
- Boiling point:
- 521.5±45.0 °C(Predicted)
- Density
- 1.570±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO: 83.33 mg/mL (301.68 mM)
- pka
- 10.65±0.40(Predicted)
- form
- Solid
- color
- Off-white to gray
- InChI
- InChI=1S/C13H9FN2O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4H2,(H,15,17,18)
- InChIKey
- MPQLCQKBYRSPNA-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=C(F)C=C2)C(=O)N1C1CCC(=O)NC1=O
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Ambeed
- Product number
- A1004509
- Product name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Purity
- 97%
- Packaging
- 250mg
- Price
- $35
- Updated
- 2021/12/16
Ambeed
- Product number
- A1004509
- Product name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Purity
- 97%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
Ambeed
- Product number
- A1004509
- Product name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Purity
- 97%
- Packaging
- 5g
- Price
- $220
- Updated
- 2021/12/16
Ambeed
- Product number
- A1004509
- Product name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Purity
- 97%
- Packaging
- 10g
- Price
- $300
- Updated
- 2021/12/16
Acrotein
- Product number
- H-7889
- Product name
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Purity
- 97%
- Packaging
- 10g
- Price
- $348.33
- Updated
- 2021/12/16
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2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Chemical Properties,Usage,Production
Description
2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione is a thalidomide analog that can be useful in PROTAC research.
Uses
Thalidomide 5'- fluoro (2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione) is a derivative of Thalidomide, commonly used as a precursor to PROTAC® Degraders that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a fluoro functional handle at a position known not to significantly affect binding to cereblon, ready for conjugation to a linker/target protein ligand.
storage
Store at +4°C
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Preparation Products And Raw materials
Raw materials
Preparation Products
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2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Suppliers
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View Lastest Price from 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione 835616-61-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-18