4-(4-Fluorobenzoyl)piperidine hydrochloride

Product Name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
CAS No.: 25519-78-2
Chemical Name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
Synonyms: BUTTPARK 99\50-17;Paliperidone Impurity 69;4-(4-FLUOROBENZOYL)PIPERIDINE HCL;4-FLUOROPHENYL 4-PIPERIDINYL METHANONE;4-(P-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE;4-(4-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE;(4-Fluorophenyl)(4-piperidyl)methanone .HCl;4-(4'-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE;(4-Fluorophenyl)-4-piperidinyl-Methanone HCl;4-(4-Fluorobenzoyl)piperidinehydrochloride97%
CBNumber: CB3328671
Molecular Formula: C12H15ClFNO
Formula Weight: 243.71
MOL File: 25519-78-2.mol

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4-(4-Fluorobenzoyl)piperidine hydrochloride Property

Melting point:: 222-224°C
Density: 1.31g/cm3 at 20℃
vapor pressure: 0-0Pa at 20-25℃
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Water (Slightly)
form: Solid
color: Pale Tan
Sensitive: Hygroscopic
InChI: InChI=1S/C12H14FNO.ClH/c13-11-3-1-9(2-4-11)12(15)10-5-7-14-8-6-10;/h1-4,10,14H,5-8H2;1H
InChIKey: GPKDBZQZPNOBGM-UHFFFAOYSA-N
SMILES: C1(C=CC(F)=CC=1)C(=O)C1CCNCC1.Cl
LogP: -1.1 at 20℃ and pH7
CAS DataBase Reference: 25519-78-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,C,Xn
Risk Statements: 36/37/38-20/21/22-22
Safety Statements: 26-36/37/39-22
Hazard Note: Irritant
HazardClass: IRRITANT, MOISTURE SENSITIVE, CORROSIVE
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC

Product number: F596720
Product name: 4-(4-Fluorobenzoyl)piperidinehydrochloride
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 005950
Product name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
Packaging: 1g
Price: $10
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-7-X1
Product name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
Purity: 97%
Packaging: 5G
Price: $23
Updated: 2021/12/16

Matrix Scientific

Product number: 005950
Product name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
Packaging: 5g
Price: $24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-7-X1
Product name: 4-(4-Fluorobenzoyl)piperidine hydrochloride
Purity: 97%
Packaging: 100g
Price: $295
Updated: 2021/12/16

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4-(4-Fluorobenzoyl)piperidine hydrochloride Chemical Properties,Usage,Production

Uses

4-(4-Fluorobenzoyl)piperidine, HCl

Uses

4-(4-Fluorobenzoyl)piperidine hydrochloride is a piperidnyl derivative used in the preparation of antiarrhythmics as well as α1-adrenoceptor and S2-receptor antagonists for circulatory diseases.

Synthesis

A solution of 70.6 of 1-acetyl-4-(4-fluorobenzoyl)piperidine in 200 ml of 6N HCl is refluxed for 2 hours. The cooled solution is extracted twice with ether, the aqueous solution basified with sodium hydroxide and then extracted with benzene. The benzene extracts are dried, filtered and the filtrate is concentrated under reduced pressure. The residual oil is dissolved in ether and HCl gas is bubbled into the solution with stirring. The salt is collected by filtration, washed with ether and dried. The salt is recrystallized from isopropanol to give the solid product of 4-(4-fluorobenzoyl)piperidine hydrochloride, mp 222°-224° C.

4-(4-Fluorobenzoyl)piperidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Fluorobenzoyl)piperidine hydrochloride Suppliers

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View Lastest Price from 4-(4-Fluorobenzoyl)piperidine hydrochloride manufacturers

Career Henan Chemical Co

Product: 4-(4-Fluorobenzoyl)piperidine hydrochloride 25519-78-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-06-24

25519-78-2, 4-(4-Fluorobenzoyl)piperidine hydrochlorideRelated Search:

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p-Fluorophenyl 4-Piperidinyl Ketone Hydrochloride

(4-Fluorophenyl)-4-piperidinyl-Methanone HCl

BUTTPARK 99\50-17

4-(4-FLUOROBENZOYL)PIPERIDINE HCL

4-(4'-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE

4-(4-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE

4-(P-FLUOROBENZOYL)PIPERIDINE HYDROCHLORIDE

(4-FLUORO-PHENYL)-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE

4-FLUOROPHENYL 4-PIPERIDINYL METHANONE

(4-FLUOROPHENYL)(4-PIPERIDYL)METHANONE HYDROCHLORIDE

p-fluorophenyl 4-piperidyl ketone hydrochloride

4-(4-Fluorobenzoyl)piperidine hydrochloride 97%

4-(4-Fluorobenzoyl)piperidinehydrochloride97%

4-Fluorophenyl 4-piperidinyl ketone hydrochloride

(4-Fluorophenyl)(4-piperidyl)methanone .HCl

Paliperidone Impurity 69

25519-78-2

C12H14FNOClH

C12H14FNOHCl

AMINE

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