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GSK9311

Product Name
GSK9311
CAS No.
1923851-49-3
Chemical Name
GSK9311
Synonyms
GSK9311;GSK 9311;GSK-9311;GSK9311 >=98% (HPLC);GSK 9311 hydrochloride;BRPF1 bromodomain inhibitor GS9311;Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxy-
CBNumber
CB33309536
Molecular Formula
C24H31N5O3
Formula Weight
437.53
MOL File
1923851-49-3.mol
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GSK9311 Property

Boiling point:
625.5±55.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 30 mg/mL (68.57 mM)
pka
8.82±0.40(Predicted)
form 
Solid
color 
White to off-white
optical activity
[α]/D 90 to 100°, c =0.3 in methanol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1984
Product name
GSK9311
Purity
≥98% (HPLC)
Packaging
5MG
Price
$115
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1984
Product name
GSK9311
Purity
≥98% (HPLC)
Packaging
25MG
Price
$423
Updated
2022/05/15
Tocris
Product number
6203
Product name
GSK9311hydrochloride
Purity
≥98%(HPLC)
Packaging
25
Price
$279
Updated
2021/12/16
Tocris
Product number
6203
Product name
GSK9311hydrochloride
Purity
≥98%(HPLC)
Packaging
5
Price
$72
Updated
2021/12/16
ChemScene
Product number
CS-6907
Product name
GSK9311
Purity
99.23%
Packaging
5mg
Price
$90
Updated
2021/12/16
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GSK9311 Chemical Properties,Usage,Production

Biological Activity

GSK9311 is a negative control for the SGC epigenetic probe GSK6853. GSK9311 exhibits 125- and 185-fold reduced potency than its structural analog GSK6853 toward BRPF1 in cell-free and cell-based assays (pIC50 = 6.0/GSK9311 vs. 8.1/GSK6853 in ligand competition binding assay by TR-FRET; IC50 = 3.7 μM/GSK9311 vs. 20 nM/GSK6853 against NanoLuc-BRPF1 bromodomain interaction with Histone H3.3-HaloTag in HEK293 cells), and therefore serves as a good inactive control compound in BRPF1 inhibition studies employing GSK6853. For characterization details of the active probe, GSK6853, please visit the GSK6853 probe summary on the Structural Genomics Consortium (SGC) website.

GSK6853, the active probe, is available from Sigma. To learn more about and purchase GSK6853, click here.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

GSK9311 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK9311 Suppliers

Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7787
Advantage
56
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1925
Advantage
55
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58

1923851-49-3, GSK9311Related Search:


  • GSK9311
  • GSK 9311;GSK-9311
  • BRPF1 bromodomain inhibitor GS9311
  • GSK 9311 hydrochloride
  • Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxy-
  • GSK9311 >=98% (HPLC)
  • 1923851-49-3