ChemicalBook > CAS DataBase List > Pidilizumab
Pidilizumab
- Product Name
- Pidilizumab
- CAS No.
- 1036730-42-3
- Chemical Name
- Pidilizumab
- Synonyms
- Pidilizumab;Research Grade Pidilizumab;Research Grade Pidilizumab (DHH02216)
- CBNumber
- CB33309804
- Formula Weight
- 0
- MOL File
- Mol file
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Pidilizumab Chemical Properties,Usage,Production
Uses
Pidilizumab (CT-011) is a humanized IgG1k anti-PD-1 monoclonal antibody. Pidilizumab acts as a DLL1 antagonist. Pidilizumab has the potential for hematologic malignancies research[1].
References
[1] Jason R Westin, et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014 Jan;15(1):69-77. DOI:10.1016/S1470-2045(13)70551-5
[2] Aline de Oliveira Albuquerque, et al. Computationally-obtained structural insights into the molecular interactions between Pidilizumab and binding partners DLL1 and PD-1. J Biomol Struct Dyn. 2022 Sep;40(14):6450-6462. DOI:10.1080/07391102.2021.1885492
Pidilizumab Preparation Products And Raw materials
Raw materials
Preparation Products
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