ChemicalBook > CAS DataBase List > 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE

Product Name
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
CAS No.
174689-39-5
Chemical Name
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
Synonyms
SR 59230A;SR59230AHCl;SR 59230A HYDROCHLORIDE;SR 59230A >=98% (HPLC), powder;(2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol;3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE;(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate;3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt;1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE;hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
CBNumber
CB3331761
Molecular Formula
C23H29NO6
Formula Weight
415.49
MOL File
174689-39-5.mol
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Property

storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO: >10mg/mL
form 
powder
color 
white
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S8688
Product name
SR 59230A
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
S8688
Product name
SR 59230A
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$228.4
Updated
2024/03/01
Tocris
Product number
1511
Product name
SR59230Ahydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$220
Updated
2021/12/16
Tocris
Product number
1511
Product name
SR59230Ahydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$926
Updated
2021/12/16
Usbiological
Product number
256751
Product name
SR 59230A hydrochloride
Packaging
10mg
Price
$466
Updated
2021/12/16
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4

Hazard

A poison.

Biological Activity

Potent and selective β 3 adrenoceptor antagonist (IC 50 values are 40, 408 and 648 nM for β 3 , β 1 and β 2 receptors respectively). Orally active in vivo . Also available as part of the β -Adrenoceptor Antagonist Tocriset™ .

Biochem/physiol Actions

SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Suppliers

China 45 Europe 1 Germany 3 Switzerland 1 United Kingdom 1 United States 6 Global 57
BIOTREND GmbH
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Fax
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Email
jaeger@biotrend.com
Country
Germany
ProdList
249
Advantage
65
Service Chemical Inc.
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Fax
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Email
sales@chemos-group.com
Country
Germany
ProdList
6350
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71
BIOTREND Chemicals AG
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Fax
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Email
info@biotrend.ch
Country
Germany
ProdList
1250
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62

174689-39-5, 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDERelated Search:

(S)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE (S)--1-AMINOTETRALINE HCL 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE (S)-(-)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL

  • 3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE
  • SR 59230A HYDROCHLORIDE
  • SR59230AHCl
  • 3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt
  • SR 59230A
  • 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
  • SR 59230A >=98% (HPLC), powder
  • (S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate
  • hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
  • (2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol
  • 174689-39-5
  • C21H27NO2HCl
  • Adrenoceptor