ChemicalBook > CAS DataBase List > Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride

Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride

Product Name
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
CAS No.
1278405-51-8
Chemical Name
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
Synonyms
CHK-IN-1;CHKIN1,CHK IN 1;Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
CBNumber
CB33339722
Molecular Formula
C18H19ClFN5OS
Formula Weight
407.8927632
MOL File
1278405-51-8.mol
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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Chemical Properties,Usage,Production

Description

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].

References

[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1

Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Suppliers

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1278405-51-8, Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochlorideRelated Search:


  • Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
  • CHK-IN-1
  • CHKIN1,CHK IN 1
  • 1278405-51-8