25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane
- Product Name
- 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane
- CAS No.
- 1056881-04-9
- Chemical Name
- 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane
- Synonyms
- mPEG8-Br;m-PEG8-bromide;octaethyleneglycolmonomethyletherbromide;25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane;2,5,8,11,14,17,20,23-Octaoxapentacosane, 25-bromo-;25-Bromo-2581114172023-octaoxapentacosane/m-PEG8-Br;mPEG8-Br/2,5,8,11,14,17,20,23-Octaoxapentacosane, 25-bromo-
- CBNumber
- CB33340212
- Molecular Formula
- C17H35BrO8
- Formula Weight
- 447.36
- MOL File
- 1056881-04-9.mol
25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane Property
- Boiling point:
- 462.5±40.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, sealed storage, away from moisture
- solubility
- Soluble in Water, DMSO, DMF, DCM
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23764
- Product name
- m-PEG8-bromide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- BP-23764
- Product name
- m-PEG8-bromide
- Purity
- 98%
- Packaging
- 1g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- AS104124
- Product name
- mPEG8-Br
- Purity
- 95+%
- Packaging
- 1g
- Price
- $421
- Updated
- 2021/12/16
- Product number
- 3664608
- Product name
- 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane
- Purity
- min.95%
- Packaging
- 5G
- Price
- $833
- Updated
- 2021/12/16
- Product number
- B-1023
- Product name
- mPEG8-Br
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $220
- Updated
- 2021/12/16
25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane Chemical Properties,Usage,Production
Description
m-PEG8-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane Preparation Products And Raw materials
Raw materials
Preparation Products
25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane Suppliers
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View Lastest Price from 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane manufacturers
- Product
- m-PEG8-Br 1056881-04-9
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-27