ChemicalBook > CAS DataBase List > ETHYL (METHYLTHIO)ACETATE
ETHYL (METHYLTHIO)ACETATE
- Product Name
- ETHYL (METHYLTHIO)ACETATE
- CAS No.
- 4455-13-4
- Chemical Name
- ETHYL (METHYLTHIO)ACETATE
- Synonyms
- FEMA 3835;ETHYL (METHYLTHIO)ACETATE;5-PHENYL-O-ANISIDINE, 98+%;ETHYL 2-(METHYLTHIO)ACETATE;Ethyl(Methylthio)acetate>Ethyl(methylthio)acetate,98%;Ethyl (methylsulfanyl)acetate;Ethyl (methylthio)acetate,95%;ETHYL ALPHA-(METHYLTHIO)ACETATE;(methylthio)-aceticaciethylester
- CBNumber
- CB3335507
- Molecular Formula
- C5H10O2S
- Formula Weight
- 134.2
- MOL File
- 4455-13-4.mol
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ETHYL (METHYLTHIO)ACETATE Property
- Boiling point:
- 70-72 °C/25 mmHg (lit.)
- Density
- 1.043 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.459(lit.)
- FEMA
- 3835 | ETHYL 2-(METHYLTHIO)ACETATE
- Flash point:
- 139 °F
- storage temp.
- 2-8°C
- form
- clear liquid
- color
- colorless
- Odor
- at 0.10 % in dipropylene glycol. sulfurous green fruity tropical
- Odor Type
- fruity
- biological source
- synthetic
- Water Solubility
- Miscible with alcohol. Immiscible with water.
- Sensitive
- Moisture Sensitive
- JECFA Number
- 475
- BRN
- 1744999
- LogP
- 1.35
- CAS DataBase Reference
- 4455-13-4(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W383503
- Product name
- Ethyl (methylthio)acetate
- Purity
- ≥98%, FG
- Packaging
- 1 unit
- Price
- $59.8
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W383503
- Product name
- Ethyl (methylthio)acetate
- Purity
- ≥98%, FG
- Packaging
- 1 unit
- Price
- $59.8
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 209716
- Product name
- Ethyl (methylthio)acetate
- Purity
- 98%
- Packaging
- 25g
- Price
- $87.5
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- W383503
- Product name
- Ethyl (methylthio)acetate
- Purity
- ≥98%, FG
- Packaging
- sample
- Price
- $59.8
- Updated
- 2024/03/01
TCI Chemical
- Product number
- M0897
- Product name
- Ethyl (Methylthio)acetate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $21
- Updated
- 2025/07/31
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ETHYL (METHYLTHIO)ACETATE Chemical Properties,Usage,Production
Chemical Properties
clear colorless to slightly yellow liquid
Chemical Properties
Ethyl-2-(methylthio)acetate has a fruity odor.
Occurrence
Reported found in melon, apple, pineapple, durian, yellow passion fruit and kiwifruit.
Uses
Ethyl (methylthio)acetate is used as an internal standard during the analytical determination of volatile sulfur compounds in port wines. Further, it is used as food flavors.
Uses
Ethyl (methylthio)acetate was used as internal standard during the analytical determination of volatile sulfur compounds in port wines.
Definition
ChEBI: Ethyl 2-(methylthio)acetate is a carboxylic ester.
Aroma threshold values
Detection: 250 ppb. Aroma characteristics at 1.0%: sweet, ethereal, rummy with a fruity sulfureous note, slightly vegetative cauliflower with a garlic nuance.
Taste threshold values
Taste characteristics at 1 to 2 ppm: sweet, fruity melon with an uplifting rummy undertone.
General Description
Natural occurrence: Apple and melon.
Biochem/physiol Actions
Taste at 1-2 ppm
Synthesis
64-17-5
2444-37-3
4455-13-4
Toluene (30 mL), ethanol (2.39 g, 169.59 mmol), and 2-(methylthio)acetic acid (15 g, 141.32 mmol) were sequentially added to a 100 mL round-bottomed flask at room temperature, followed by the addition of p-toluenesulfonic acid monohydrate (4.03 g, 21.20 mmol) as a catalyst. The reaction mixture was gently heated to reflux and the dehydration reaction was carried out for 3 to 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, followed by addition of triethylamine (2.86 g, 28.26 mmol) to neutralize the acidic catalyst and silica gel for adsorption. After brief stirring, the silica gel was removed by filtration. The filtrate was distilled under reduced pressure to remove the solvent and finally purified by distillation to give ethyl (methylthio)acetate (14.81 g, 78% yield).
References
[1] Patent: US2010/324314, 2010, A1. Location in patent: Page/Page column 15-16
[2] Combinatorial Chemistry and High Throughput Screening, 2011, vol. 14, # 2, p. 132 - 137
ETHYL (METHYLTHIO)ACETATE Preparation Products And Raw materials
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Preparation Products
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View Lastest Price from ETHYL (METHYLTHIO)ACETATE manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- ETHYL (METHYLTHIO)ACETATE 4455-13-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-27
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Ethyl (methylthio)acetate 4455-13-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 100KGS
- Release date
- 2021-06-29
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- Ethyl (METHYLTHIO) Acetate 4455-13-4
- Price
- US $79.00-38.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-12-20
4455-13-4, ETHYL (METHYLTHIO)ACETATERelated Search:
1,5,2,4-Dioxadithiane 2,2,4,4-tetraoxide
2-(TERT-BUTYLAMINO)ETHYL METHACRYLATE
Diethyl methylmalonate
(R)-BETA-HYDROXY-BETA-METHYL-DELTA-VALEROLACTONE
ETHYL (METHYLTHIO)ACETATE
ETHYL METHANESULFONYLACETATE
ETHYL 2-METHYL-2-(METHYLTHIO)PROPIONATE
S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
ETHYL 1,3-DITHIOLANE-2-CARBOXYLATE
Ethyl 1,3-dithiane-2-carboxylate
METHYLENEBIS(THIOGLYCOLIC ACID DI-N-BUTYL ESTER)
5-PHENYL-O-ANISIDINE
(METHYLTHIO)ACETIC ACID
ETHYL 2-[(4-METHYLPHENYL)SULFONYL]ACETATE
GLYOXYLIC ACID ETHYL ESTER DIETHYL MERCAPTAL
PHENYLSULFONYLACETIC ACID ETHYL ESTER
ETHYL 2-[(2-METHYL-1H-INDOL-3-YL)THIO]ACETATE
DIETHYL METHYLENEBIS(2-THIOACETATE)