2-Methyl-3-biphenylmethanol

Product Name: 2-Methyl-3-biphenylmethanol
CAS No.: 76350-90-8
Chemical Name: 2-Methyl-3-biphenylmethanol
Synonyms: Bifenthrin alcohol;Biphenyl alcohol;biphenylmethyanol;2-METHYLBIPHENYL-3-METHANOL;2-methyl-3-biphenylmethyanol;3-HYDROXYMETHYL-2-METHYLBIPHENYL;2-Methyl-3-biphenylm;2-METHYL-3-BIPHENYLMETHANOL;2-Methyl-3-phenylbenzyl Alcohol;2-METHYL-3-BIPHENYLMETHANOL 97%
CBNumber: CB3339318
Molecular Formula: C14H14O
Formula Weight: 198.26
MOL File: 76350-90-8.mol

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2-Methyl-3-biphenylmethanol Property

Melting point:: 73-76 °C(lit.)
Boiling point:: 330.9±11.0 °C(Predicted)
Density: 1.072±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.28±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C14H14O/c1-11-13(10-15)8-5-9-14(11)12-6-3-2-4-7-12/h2-9,15H,10H2,1H3
InChIKey: BGTLHJPGBIVQLJ-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)=CC=CC(CO)=C1C
CAS DataBase Reference: 76350-90-8(CAS DataBase Reference)
EPA Substance Registry System: [1,1'-Biphenyl]-3-methanol, 2-methyl- (76350-90-8)

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Safety

WGK Germany: 3
HS Code: 2906290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: H0777
Product name: 3-Hydroxymethyl-2-methylbiphenyl
Purity: >98.0%(GC)
Packaging: 25g
Price: $157
Updated: 2025/07/31

TRC

Product number: M294130
Product name: 2-Methyl-3-biphenylmethanol
Packaging: 50g
Price: $260
Updated: 2021/12/16

TRC

Product number: M294130
Product name: 2-Methyl-3-biphenylmethanol
Packaging: 250g
Price: $525
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0010544
Product name: 3-HYDROXYMETHYL-2-METHYLBIPHENYL
Purity: 95.00%
Packaging: 100MG
Price: $693
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0010544
Product name: 3-HYDROXYMETHYL-2-METHYLBIPHENYL
Purity: 95.00%
Packaging: 1G
Price: $1501.5
Updated: 2021/12/16

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2-Methyl-3-biphenylmethanol Chemical Properties,Usage,Production

Description

2-Methyl-3-biphenylmethanol is a pharmaceutical intermediate and organic chemical synthesis reagent, which can be used in the preparation of drugs such as Bifenthrin and PD-L1 inhibitors, and also in the synthesis of other organic compounds such as 2-methyl-3-phenylphenethylboronic acid pinacol ester, biphenyl-1,2,3-triazole couplings and biphenyl alcohols.

Chemical Properties

white to light yellow crystal powde

Uses

Bifenthrin intermediate.

Synthesis

Carrying out a Suzuki coupling reaction between 3-bromo-2-methylbenzoic acid and phenyl substituted boric acid or phenyl substituted borate to obtain 3-phenyl-2-methylbenzoic acid, and then carrying out a reduction reaction to obtain 2-Methyl-3-biphenylmethanol, wherein the Suzuki coupling reaction is carried out at 10-150°C for 1-12 hours under the action of an alkali. 3-phenyl-2-methylbenzoic acid can be directly reduced with a reducing agent such as borane and lithium aluminium hydride to obtain 2-Methyl-3-biphenylmethanol.

References

[1] Journal of Medicinal Chemistry, 2017, vol. 60, # 13, p. 5857 - 5867
[2] Patent: WO2018/200571, 2018, A1. Location in patent: Page/Page column 44-45
[3] Patent: WO2015/34820, 2015, A1. Location in patent: Page/Page column 42
[4] Patent: US2015/291549, 2015, A1. Location in patent: Paragraph 0210; 0211
[5] Patent: WO2017/118762, 2017, A1. Location in patent: Page/Page column 39; 40

2-Methyl-3-biphenylmethanol Preparation Products And Raw materials

Raw materials

Copper(I) Cyanide Copper Grignard reagent 2-Methylbenzyl alcohol 2-Methyl-3-nitrobenzyl alcohol Biphenyl Potassium iodide 3-Aminobenzylalcohol Paraformaldehyde Bromobenzene 3-CHLORO-2-METHYLBIPHENYL Tetrahydrofuran Magnesium

Preparation Products

Bifenthrin

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2-Methyl-3-biphenylmethanol Suppliers

Americas 1 Canada 2 China 267 Europe 1 Germany 4 India 12 Japan 3 Switzerland 1 Ukraine 1 United Kingdom 11 United States 21 Global 324

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View Lastest Price from 2-Methyl-3-biphenylmethanol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Methyl-3-biphenylmethanol 76350-90-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-01

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Methyl-3-biphenylmethanol 76350-90-8
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methyl-3-biphenylmethanol 76350-90-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-12

76350-90-8, 2-Methyl-3-biphenylmethanolRelated Search:

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2-Methyl-3-biphenylm

2-Methyl-3-phenylbenzyl Alcohol

[1,1'-Biphenyl]-3-Methanol,2-Methyl-

Bifenthrin alcohol metabolite, 10 μg /μL in cyclohexane

(2-Methyl[1,1'-biphenyl]- 3-yl) methanol (bifenthrin alcohol, BFA, BA)

2-METHYLBIPHENYL-3-METHANOL

2-METHYL-3-BIPHENYLMETHANOL

3-HYDROXYMETHYL-2-METHYLBIPHENYL

2-methyl-3-biphenylmethyanol

Bifenthrin alcohol

2-Methyl-[1,1'-Biphenyl]-3-Methanol

2-METHYL-3-BIPHENYLMETHANOL 97%

2-Methyl-3-hydroxymethyldiphenyl

3-(Hydroxymethyl)-2-methyl-1,1-biphenyl

(2-methyl-3-phenylphenyl)methanol

3-HYDROXYMETHYL-2-METHYLBIPHENYL 98+%

3-Hydroxymerhyl-2-methylbiphenyl

3-Hydroxymethyl-2-methylbiphenyl&gt

Biphenyl alcohol

biphenylmethyanol

2-Methyl-3-biphenylmethanol 76350-90-8

3-Hydroxymethyl-2-methylbiphenyl, ≥ 98.0%

(2-Methyl-[1,1'-biphenyl]-3-yl)methanol

2-Methyl[1,1'-biphenyl]-3-methanol

Bifenthrin-alcohol metabolite in Cyclohexane

LA10584010CY Bifenthrin-alcohoLmetabolitE10μg

76350-90-8

76350-80-9

C6H5C6H3CH3CH2OH

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