MONOSIALOGANGLIOSIDE GM3
- Product Name
- MONOSIALOGANGLIOSIDE GM3
- CAS No.
- 54827-14-4
- Chemical Name
- MONOSIALOGANGLIOSIDE GM3
- Synonyms
- GM3 NA;Hematoside;Ganglioside M3;GM1-GANGLIOSIDE;GM3 (NH4+ SALT);Ganglioside GM3;II3NEUAC-GGOSE4CER;GANGLIOSIDE GM3(18, 2);GM3-Ganglioside sodium;Sialosyllactosylceramide
- CBNumber
- CB3344558
- Molecular Formula
- C64H118N2O21.H3N
- Formula Weight
- 1268.66
- MOL File
- 54827-14-4.mol
MONOSIALOGANGLIOSIDE GM3 Property
- storage temp.
- −20°C
- solubility
- chloroform/methanol/water (9.5:9.5:1): 20mg/mLclear, colorless to light yellow
- form
- lyophilized powder
- color
- White
Safety
- WGK Germany
- 3
- F
- 10-21
N-Bromosuccinimide Price
- Product number
- G5642
- Product name
- Monosialoganglioside GM3 from canine blood
- Purity
- ≥98%, lyophilized powder
- Packaging
- 0.5mg
- Price
- $490
- Updated
- 2024/03/01
- Product number
- G5642
- Product name
- Monosialoganglioside GM3 from canine blood
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $804
- Updated
- 2024/03/01
- Product number
- 15587
- Product name
- Ganglioside GM3 (sodium salt)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $238
- Updated
- 2024/03/01
- Product number
- M567140
- Product name
- MonosialogangliosideGM3SodiumSalt
- Packaging
- 1mg
- Price
- $920
- Updated
- 2021/12/16
- Product number
- 297092
- Product name
- GM1-Ganglioside
- Packaging
- 500ug
- Price
- $1593
- Updated
- 2021/12/16
MONOSIALOGANGLIOSIDE GM3 Chemical Properties,Usage,Production
Uses
Monosialoganglioside GM3 can have anti-tumor effects by regulating cell apoptosis, angiogenesis. Monosialoganglioside GM3 can also regulate peripheral insulin receptor signaling and increases in GM3 in adipose tissue of obese humans may contribute to insulin resistance.
Uses
Monosialoganglioside GM3 from canine blood has been used as a reference standard in high-performance thin-layer chromatography (HPTLC) to analyze ganglioside signatures of prostate cancer (CaP) cells. It has also been used to determine ganglioside-binding profiles of methylotrophic yeast (Pichia pastoris) secreted cholera toxin B subunit (PpCTB) by enzyme-linked immunosorbent assay (ELISA).
General Description
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
Monosialoganglioside GM3 has a potential role in cancer development and progression. Increased expression of GM3 has been observed in various types of cancer. Hence, it is used as a tumor-associated carbohydrate antigen during cancer vaccine development.
MONOSIALOGANGLIOSIDE GM3 Preparation Products And Raw materials
Raw materials
Preparation Products
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