MONOSIALOGANGLIOSIDE GM3

Product Name: MONOSIALOGANGLIOSIDE GM3
CAS No.: 54827-14-4
Chemical Name: MONOSIALOGANGLIOSIDE GM3
Synonyms: GM3 NA;Hematoside;Ganglioside M3;GM1-GANGLIOSIDE;GM3 (NH4+ SALT);Ganglioside GM3;II3NEUAC-GGOSE4CER;GANGLIOSIDE GM3(18, 2);GM3-Ganglioside sodium;Sialosyllactosylceramide
CBNumber: CB3344558
Molecular Formula: C64H118N2O21.H3N
Formula Weight: 1268.66
MOL File: 54827-14-4.mol

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MONOSIALOGANGLIOSIDE GM3 Property

storage temp.: −20°C
solubility: chloroform/methanol/water (9.5:9.5:1): 20mg/mLclear, colorless to light yellow
form: lyophilized powder
color: White

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Safety

WGK Germany: 3
F: 10-21

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G5642
Product name: Monosialoganglioside GM3 from canine blood
Purity: ≥98%, lyophilized powder
Packaging: 0.5mg
Price: $490
Updated: 2024/03/01

Sigma-Aldrich

Product number: G5642
Product name: Monosialoganglioside GM3 from canine blood
Purity: ≥98%
Packaging: 1mg
Price: $804
Updated: 2024/03/01

Cayman Chemical

Product number: 15587
Product name: Ganglioside GM3 (sodium salt)
Purity: ≥98%
Packaging: 1mg
Price: $238
Updated: 2024/03/01

TRC

Product number: M567140
Product name: MonosialogangliosideGM3SodiumSalt
Packaging: 1mg
Price: $920
Updated: 2021/12/16

Usbiological

Product number: 297092
Product name: GM1-Ganglioside
Packaging: 500ug
Price: $1593
Updated: 2021/12/16

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MONOSIALOGANGLIOSIDE GM3 Chemical Properties,Usage,Production

Uses

Monosialoganglioside GM3 can have anti-tumor effects by regulating cell apoptosis, angiogenesis. Monosialoganglioside GM3 can also regulate peripheral insulin receptor signaling and increases in GM3 in adipose tissue of obese humans may contribute to insulin resistance.

Uses

Monosialoganglioside GM3 from canine blood has been used as a reference standard in high-performance thin-layer chromatography (HPTLC) to analyze ganglioside signatures of prostate cancer (CaP) cells. It has also been used to determine ganglioside-binding profiles of methylotrophic yeast (Pichia pastoris) secreted cholera toxin B subunit (PpCTB) by enzyme-linked immunosorbent assay (ELISA).

General Description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

Monosialoganglioside GM3 has a potential role in cancer development and progression. Increased expression of GM3 has been observed in various types of cancer. Hence, it is used as a tumor-associated carbohydrate antigen during cancer vaccine development.

MONOSIALOGANGLIOSIDE GM3 Preparation Products And Raw materials

Raw materials

Preparation Products

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MONOSIALOGANGLIOSIDE GM3 Suppliers

China 28 Germany 1 India 1 Japan 1 Sweden 1 Switzerland 2 United Kingdom 3 United States 13 Global 50

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54827-14-4, MONOSIALOGANGLIOSIDE GM3Related Search:

MONOSIALOGANGLIOSIDE GM2 (NH4+ SALT) MONOSIALOGANGLIOSIDE-GM2-PYRENE LABELED FUCOSYLATED MONOSIALOGANGLIOSIDE GM1 (NH4+ SALT) MONOSIALOGANGLIOSIDE GM4, HUMAN GANGLIOSIDE GM1, AMMONIUM SALT, BOVINE GANGLIOSIDE GM2 SODIUM SALT LYSO-MONOSIALOGANGLIOSIDE GM1 MONOSIALOGANGLIOSIDE GM1, INNER ESTER MONOSIALOGANGLIOSIDE-GM1-PYRENE LABELED LYSO-MONOSIALOGANGLIOSIDE GM1 (NH4+ SALT) MONOSIALOGANGLIOSIDE GM4 MONOSIALOGANGLIOSIDE-GM3-PYRENE LABELED myralact C22 Ceramide MONOSIALOGANGLIOSIDE GM3

Monosialoganglioside GM3, Bovine (NH4+ salt)

Monosialoganglioside GM3 (bovine)(aMMoniuM salt)

Ganglioside M3

Hematoside

Sialosyllactosylceramide

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-octadecanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/18:0)

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-icosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/20:0)

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-docosanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/22:0)

GANGLIOSIDE GM3(18, 2)

GANGLIOSIDE GM3, MONOSIALO

GANGLIOSIDE GM3 SODIUM SALT

MONOSIALOGANGLIOSIDE GM3 SODIUM SALT

MONOSIALOGANGLIOSIDE GM3

MONOSIALOGANGLIOSIDE GM3, BOVINE

MONOSIALOGANGLIOSIDE GM3, HUMAN

MONOSIALOGANGLIOSIDE GM3 NA (BOVINE)

MONOSIALOGANGLIOSIDE GM3 (NH4+ SALT)

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-tetracosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/24:0)

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-((Z)-tetracos-15-enamido)octadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/24:1(15Z))

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-pentacosanamidooctadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/25:0)

(2S,4S,5R)-5-ethanamido-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-hexacosanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/26:0)

(2S,4S,5R)-5-ethanamido-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-((Z)-hexacos-17-enamido)-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/26:1(17Z)))

GM3-Ganglioside sodium

GM1-GANGLIOSIDE

GM3 NA

GM3 (NH4+ SALT)

II3NEUAC-GGOSE4CER

ganglioside monosialoganglioside-gm3

Monosialoganglioside GM3 bovine brain

MONOSIALOGANGLIOSIDE-GM3 CELL CULTURE*TE STED

Ganglioside GM3

monosialoganglioside gm3 from bovine brain

monosialoganglioside gm3 from canine blood

GANGLIOSIDEGM3SODIUMSALT,BOVINEBRAIN

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-4,5-dihydroxy-6-((2S,3R,E)-3-hydroxy-2-((Z)-octadec-9-enamido)octadec-4-enyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 ((d18:1/9Z-18:1)

(2S,4S,5R)-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-dodecanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-5-ethanamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/12:0)

(2S,4S,5R)-5-ethanamido-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R,6R)-6-((2S,3R,E)-2-hexadecanamido-3-hydroxyoctadec-4-enyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid

Ganglioside GM3 (d18:1/16:0)

Ganglioside GM3 Mixture (sodium salt)

Ganglioside GM3 Mixture (ammonium salt)

Ganglioside GM3 (bovine brain) (sodium salt)

Sodium N-((3R,6S)-6-carboxy-6-(((2S,4S,5R)-2-(((2S,3S,6R)-4,5-dihydroxy-6-(((2S,3R,E)-3-hydroxy-2-stearamidooctadec-4-en-1-yl)oxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-2-((1S,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-3-yl)acetimidate

54827-14-4

C53H96N2O21

C57H104N2O21

C59H108N2O21

C61H112N2O21

C63H116N2O21