4-Nonylphenylboronic acid
- Product Name
- 4-Nonylphenylboronic acid
- CAS No.
- 256383-45-6
- Chemical Name
- 4-Nonylphenylboronic acid
- Synonyms
- AKOS BRN-0129;FAAH/MAGL-IN-4;Nonylbenzeneboronic acid;(4-nonylphenyl)boronicaci;4-Nonylphenylboronic acid;4-N-nonylphenylbronic acid;4-N-NONYLPHENYLBORONIC ACID;1-Borono-4-(non-1-yl)benzene;4-N-NONYLBENZENEBORONIC ACID;4-(Non-1-yl)benzeneboronic acid
- CBNumber
- CB3346668
- Molecular Formula
- C15H25BO2
- Formula Weight
- 248.17
- MOL File
- 256383-45-6.mol
4-Nonylphenylboronic acid Property
- Melting point:
- 82-85°C
- Boiling point:
- 385.3±35.0 °C(Predicted)
- Density
- 0.97±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 30 mg/ml)
- pka
- 8.72±0.16(Predicted)
- form
- solid
- color
- White
- Water Solubility
- Insoluble in water.
- BRN
- 8215118
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
- CAS DataBase Reference
- 256383-45-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- L17753
- Product name
- 4-n-Nonylbenzeneboronic acid, 98+%
- Packaging
- 1g
- Price
- $95.65
- Updated
- 2024/03/01
- Product number
- L17753
- Product name
- 4-n-Nonylbenzeneboronic acid, 98+%
- Packaging
- 5g
- Price
- $412
- Updated
- 2024/03/01
- Product number
- 13140
- Product name
- 4-(n-nonyl) Benzeneboronic Acid
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $19
- Updated
- 2024/03/01
- Product number
- 13140
- Product name
- 4-(n-nonyl) Benzeneboronic Acid
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- 13140
- Product name
- 4-(n-nonyl) Benzeneboronic Acid
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $39
- Updated
- 2024/03/01
4-Nonylphenylboronic acid Chemical Properties,Usage,Production
Description
Nonylbenzeneboronic acid (CAS 256383-45-6) is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH, the enzyme which hydrolyzes and deactivates anandamide), IC50=9.1 nM1. Also inhibits monoacylglycerol lipase (MAGL, the enzyme which hydrolyzes 2-arachidonoyl-glycerol), IC50=7.9 μM.1
Uses
4-n-Nonylbenzeneboronic acid is a potent inhibitor of fatty acid amide hydrolase. It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG).
in vitro
4-(n-nonyl) benzeneboronic acid was synthezed as a potent inhibitor of faah, with an ic50 of 9.1 nm. 4-(n-nonyl) benzeneboronic acid was also found to be able to inhibit magl, which could hydrolyze 2-arachidonoyl glycerol, but at around 1000-fold higher concentration. moreover, it was found that as the most potent para-substituted compound, 4-(n-nonyl) benzeneboronic acid showed rather high pka of 9.1. in addition, the molecular docking was utilized to gain insight on the faah binding mode of 4-(n-nonyl) benzeneboronic acid and a putative binding mode was observed [1].
IC 50
9.1 nm
References
1) Minkkila?et al.?(2008),?Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase; J. Med. Chem.,?51?7057
4-Nonylphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Nonylphenylboronic acid Suppliers
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30132
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44751
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35906
- Advantage
- 56
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 13355009207 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18739
- Advantage
- 57
- Tel
- 021-52212593 13761626812
- Fax
- +86 (21) 51062076
- sales@nuohey.com
- Country
- China
- ProdList
- 7135
- Advantage
- 60
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9352
- Advantage
- 58
- Tel
- 021-24206007 13764915196
- Fax
- 86-021-23027023
- sales@balmxy.com
- Country
- China
- ProdList
- 6719
- Advantage
- 55
- Tel
- 027-67849912
- Fax
- 027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 9150
- Advantage
- 60