CGS 15943

Product Name: CGS 15943
CAS No.: 104615-18-1
Chemical Name: CGS 15943
Synonyms: CGS 15943;CGS-15943A;CGS-15943 solid;CGS-15943 ADENOSINE A1 RECEPTOR;9-CHLORO-2-(2-FURYL)(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-AMINE;9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine;9-Chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine;9-CHLORO-2-(2-FURANYL)-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE;[1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-;9-Chloro-5,6-dihydro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-imine
CBNumber: CB3351424
Molecular Formula: C13H8ClN5O
Formula Weight: 285.69
MOL File: 104615-18-1.mol

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CGS 15943 Property

Melting point:: 278-279 °C
Density: 1.72±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: DMSO: >16 mg/mL
form: solid
pka: 1.23±0.30(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C199
Product name: CGS-15943
Purity: solid
Packaging: 25mg
Price: $160
Updated: 2024/03/01

Alfa Aesar

Product number: J61313
Product name: CGS 15943, 99+%
Packaging: 10mg
Price: $94.8
Updated: 2021/12/16

Alfa Aesar

Product number: J61313
Product name: CGS 15943, 99+%
Packaging: 50mg
Price: $327
Updated: 2021/12/16

Cayman Chemical

Product number: 22073
Product name: CGS 15943
Purity: ≥95%
Packaging: 5mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 22073
Product name: CGS 15943
Purity: ≥95%
Packaging: 10mg
Price: $62
Updated: 2024/03/01

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CGS 15943 Chemical Properties,Usage,Production

Uses

Potent adenosine receptor antagonist

Definition

ChEBI: A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosi e A2A receptors.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 27, p. 1549, 1990 DOI: 10.1002/jhet.5570270605

Biological Activity

Potent adenosine receptor antagonist (K i values are 3.5, 4.2, 16 and 51 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively). Orally active in vivo .

Biochem/physiol Actions

CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.

storage

Store at RT

CGS 15943 Preparation Products And Raw materials

Raw materials

Preparation Products

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CGS 15943 Suppliers

China 59 Europe 1 Germany 2 Switzerland 1 United Kingdom 2 United States 11 USA 1 Global 77

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
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Sigma-Aldrich

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Email: orderCN@merckgroup.com
Country: China
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Shanghai Lollane Biological Technology Co.,Ltd.

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Country: China
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Advantage: 55

Shanghai Synchem Pharma Co., ltd

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Email: synchempharma@aliyun.com
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Pharmacodia (Beijing) Co.,Ltd

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Shanghai EFE Biological Technology Co., Ltd.

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Changzhou PBpharmaceutical R&D Co.,Ltd

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ShangHai Biochempartner Co.,Ltd

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Shanghai Rechem science Co., Ltd.

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104615-18-1, CGS 15943Related Search:

1H-1,2,4-Triazole-1-carboximidamide hydrochloride N,N-didemethylchlordimeform MRS 1220 N-(4-Chlorophenyl)guanidine CGS 15943

9-CHLORO-2-(2-FURYL)(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-AMINE

9-CHLORO-2-(2-FURANYL)-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE

CGS-15943 ADENOSINE A1 RECEPTOR

CGS 15943

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine

9-Chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine

9-Chloro-5,6-dihydro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-imine

CGS-15943A

[1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-

CGS-15943 solid

Adenosine Receptor,CGS-15943,Phosphoinositide 3-kinase,P1 receptor,PI3K,inhibit,CGS15943,CGS 15943,Inhibitor

104615-18-1

C13H8ClN5O

Adenosine receptor