ChemicalBook > CAS DataBase List > 5-AMINO-2-METHYLBENZONITRILE

5-AMINO-2-METHYLBENZONITRILE

Product Name: 5-AMINO-2-METHYLBENZONITRILE
CAS No.: 50670-64-9
Chemical Name: 5-AMINO-2-METHYLBENZONITRILE
Synonyms: TIMTEC-BB SBB002351;5-Amino-o-tolunitrile;4-AMino-2-cyanotoluene;5-AMINO-2-METHYLBENZONITRILE;2-METHYL-5-AMINOBENZONITRILE;Benzonitrile, 5-amino-2-methyl-;5-Amino-2-methylbenzonitrile 97%;5-Amino-2-methylbenzonitrile ,98%;5-AMINO-2-METHYLBENZENECARBONITRILE;3-Cyano-4-methylaniline, 4-Amino-2-cyanotoluene
CBNumber: CB3359187
Molecular Formula: C8H8N2
Formula Weight: 132.16
MOL File: 50670-64-9.mol

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5-AMINO-2-METHYLBENZONITRILE Property

Melting point:: 88-91 °C(lit.)
Boiling point:: 110°C/22mmHg(lit.)
Density: 1.1083 (rough estimate)
refractive index: 1.6231 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: Powder
color: Yellow to brown
InChIKey: YDZVQWCVKXYGIU-UHFFFAOYSA-N
CAS DataBase Reference: 50670-64-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN 3439 6.1/PG III
WGK Germany: 3
Hazard Note: Toxic
HazardClass: IRRITANT
HazardClass: 6.1
PackingGroup: III
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 549584
Product name: 5-Amino-2-methylbenzonitrile
Purity: 97%
Packaging: 25g
Price: $133
Updated: 2023/01/07

TCI Chemical

Product number: A2814
Product name: 5-Amino-2-methylbenzonitrile
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: A2814
Product name: 5-Amino-2-methylbenzonitrile
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $47
Updated: 2025/07/31

TRC

Product number: A898173
Product name: 5-Amino-2-methylbenzonitrile
Packaging: 10g
Price: $155
Updated: 2021/12/16

TRC

Product number: A898173
Product name: 5-Amino-2-methylbenzonitrile
Packaging: 5g
Price: $90
Updated: 2021/12/16

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5-AMINO-2-METHYLBENZONITRILE Chemical Properties,Usage,Production

Uses

5-Amino-2-methylbenzonitrile may be used as a starting material for the synthesis of 5-iodo-2-methylbenzonitrile and 5-hydroxy-2-methylbenzonitrile. It may also be used in the preparation of 5-(2,4-dioxothiazolidin-3-yl)-2-methylbenzonitrile by reacting with thioglycolic acid methyl ester in the presence of 1,1′-carbonyldiimidazole.

Synthesis

939-83-3

50670-64-9

Step 2: Synthesis of 5-amino-2-methylbenzonitrile: 2-methyl-5-nitrobenzonitrile (25.0 g, 154 mmol), 10% palladium carbon catalyst (2.5 g), ethyl acetate (150 mL) and ethanol (150 mL) were mixed. The reaction mixture was stirred under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a pad of diatomaceous earth followed by concentration of the filtrate to afford 5-amino-2-methylbenzenecarbonitrile (19.6 g, 96% yield), the product was a tan solid. Mass spectral analysis showed m/e = 133 (M + H). Reference: Scholz, D. et al, J. Med. Chem. 41, 1050-1059 (1998).

References

[1] Patent: WO2005/97750, 2005, A1. Location in patent: Page/Page column 69
[2] Organic Letters, 2017, vol. 19, # 18, p. 4746 - 4749
[3] Organic Letters, 2003, vol. 5, # 7, p. 1131 - 1134
[4] Journal of Materials Chemistry, 2011, vol. 21, # 26, p. 9523 - 9531
[5] Patent: US5596006, 1997, A

5-AMINO-2-METHYLBENZONITRILE Preparation Products And Raw materials

Raw materials

ZINC Ethanol Ethyl acetate Nitric acid Methanol Sodium hydroxide o-Tolunitrile Sulfuric acid

Preparation Products

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5-AMINO-2-METHYLBENZONITRILE Suppliers

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View Lastest Price from 5-AMINO-2-METHYLBENZONITRILE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-AMINO-2-METHYLBENZONITRILE 50670-64-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-14

Honest Joy Holdings Limited

Product: 5-AMino-2-Methylbenzonitrile 50670-64-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100 tons
Release date: 2022-01-14

Career Henan Chemical Co

Product: 5-AMINO-2-METHYLBENZONITRILE 50670-64-9
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-09

50670-64-9, 5-AMINO-2-METHYLBENZONITRILERelated Search:

5-AMINO-2-METHYLBENZONITRILE 4-Nitrophthalonitrile 4-Aminophthalonitrile 2-METHYL-5-NITROBENZONITRILE 2-AMINO-4-METHYLBENZONITRILE 3-Amino-4-methylbenzonitrile 4-AMINO-3-METHYLBENZONITRILE, 98+%,4-AMINO-3-METHYLBENZONITRILE N-(3-CYANO-4-METHYLPHENYL)-N'-CYCLOHEXYLTHIOUREA 5-[(2-HYDROXYBENZYL)AMINO]-2-METHYLBENZENECARBONITRILE 2-CYANO-4,6-DINITRO-1-METHYLBENZENE 4-amino-2-methylbenzonitrile 2-AMINO-6-METHYLBENZONITRILE,2-AMINO-6-METHYLBENZONITRILE PURUM 97% 4,5-DIAMINO-2-CYANOPHENYL CYANIDE 5-[((4-[(4-FLUOROBENZYL)OXY]PHENYL)METHYLENE)AMINO]-2-METHYLBENZENECARBONITRILE TIMTEC-BB SBB001127 N-benzyl-N'-(3-cyano-4-methylphenyl)thiourea (3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)-N-(3-NITRILO-4-METHYLPHENYL)FORMAMIDE N-(3-CYANO-4-METHYLPHENYL)-N'-(4-ETHOXYPHENYL)THIOUREA

5-AMINO-2-METHYLBENZENECARBONITRILE

5-AMINO-2-METHYLBENZONITRILE

TIMTEC-BB SBB002351

2-METHYL-5-AMINOBENZONITRILE

5-Amino-2-methylbenzonitrile ,98%

3-Cyano-4-methylaniline, 4-Amino-2-cyanotoluene

4-AMino-2-cyanotoluene

5-Amino-2-methylbenzonitrile 97%

Benzonitrile, 5-amino-2-methyl-

5-Amino-o-tolunitrile

50670-64-9

Cyanides/Nitriles

Organic Building Blocks

Nitrogen Compounds

C8 to C9

Building Blocks

Aromatic Nitriles

C8 to C9

Cyanides/Nitriles

Nitrogen Compounds