N-NITROSOPIPERIDINE
- Product Name
- N-NITROSOPIPERIDINE
- CAS No.
- 100-75-4
- Chemical Name
- N-NITROSOPIPERIDINE
- Synonyms
- NPI;NPIP;tl266;n-pip;No-Pip;NSC 138;N-N-Pip;N-Nitrosopi;Nitrosopiperidin;NITROSOPIPERIDINE
- CBNumber
- CB3374481
- Molecular Formula
- C5H10N2O
- Formula Weight
- 114.15
- MOL File
- 100-75-4.mol
N-NITROSOPIPERIDINE Property
- Melting point:
- 170℃ (decomposition)
- Boiling point:
- 219℃
- Density
- 1.06 g/mL(lit.)
- refractive index
- 1.4933 (589.3 nm 19℃)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- buffered aqueous solution
- pka
- -3.18±0.20(Predicted)
- color
- Light-yellow oil
- Water Solubility
- 76.48g/L(24 ºC)
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 100-75-4(CAS DataBase Reference)
- IARC
- 2B (Vol. 17, Sup 7) 1987
- EPA Substance Registry System
- N-Nitrosopiperidine (100-75-4)
Safety
- Hazard Codes
- T,F
- Risk Statements
- 25-40-39/23/24/25-23/24/25-11
- Safety Statements
- 53-23-26-36/37/39-45-36/37-16-9
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 3
- RTECS
- TN2100000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 100-75-4(Hazardous Substances Data)
- Toxicity
- LD50 orl-rat: 200 mg/kg ZEKBAI 69,103,67
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H370Causes damage to organs
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P311Call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- SAB1300842
- Product name
- Anti-NP1(Nptx1) (C-term) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 100μg
- Price
- $441
- Updated
- 2024/03/01
- Product number
- 40458
- Product name
- 1-Nitrosopiperidine solution
- Purity
- certified reference material, 5000?μg/mL in methanol
- Packaging
- 1mL
- Price
- $62.3
- Updated
- 2024/03/01
- Product number
- 40458
- Product name
- 1-Nitrosopiperidine solution
- Purity
- certified reference material, 5000 μg/mL in methanol
- Packaging
- 40458
- Price
- $47.2
- Updated
- 2021/12/16
- Product number
- N545370
- Product name
- N-Nitrosopiperidine
- Packaging
- 500mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 156066
- Product name
- Neuronal Pentraxin I
- Packaging
- 10ug
- Price
- $355
- Updated
- 2021/12/16
N-NITROSOPIPERIDINE Chemical Properties,Usage,Production
Chemical Properties
light yellow oily liquid
Chemical Properties
N-Nitrosopiperidine is a clear, yellow, oily liquid.
Uses
A carcinogenic nitrosocompound.
Definition
ChEBI: N-nitrosopiperidine is a nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. It has a role as a carcinogenic agent, an apoptosis inducer, a mutagen and an environmental contaminant. It is a nitrosamine and a piperidine.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 36, p. 459, 1988 DOI: 10.1248/cpb.36.459
General Description
Light yellow oil or liquid. May be a carcinogen.
Air & Water Reactions
Water soluble.
Reactivity Profile
N-NITROSOPIPERIDINE may react with strong oxidizing agents, especially peroxyacids. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOPIPERIDINE emits highly toxic fumes.
Fire Hazard
Flash point data are not available for N-NITROSOPIPERIDINE, but N-NITROSOPIPERIDINE is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Potential Exposure
N-Nitrosopiperidine is found in some foods and tobacco smoke. Used as a research chemical.
Carcinogenicity
N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required
Incompatibilities
Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Reaction with aliphatic amines can release carcinogenic nitrosamines. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light and UV may cause decomposition
Waste Disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.
N-NITROSOPIPERIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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