N-NITROSOPIPERIDINE

ChemicalBook > CAS DataBase List > N-NITROSOPIPERIDINE

N-NITROSOPIPERIDINE

Product Name: N-NITROSOPIPERIDINE
CAS No.: 100-75-4
Chemical Name: N-NITROSOPIPERIDINE
Synonyms: NPI;NPIP;tl266;n-pip;No-Pip;NSC 138;N-N-Pip;N-Nitrosopi;Nitrosopiperidin;NITROSOPIPERIDINE
CBNumber: CB3374481
Molecular Formula: C5H10N2O
Formula Weight: 114.15
MOL File: 100-75-4.mol

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N-NITROSOPIPERIDINE Property

Melting point:: 170℃ (decomposition)
Boiling point:: 219℃
Density: 1.06 g/mL(lit.)
refractive index: 1.4933 (589.3 nm 19℃)
Flash point:: 11 °C
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: buffered aqueous solution
pka: -3.18±0.20(Predicted)
color: Light-yellow oil
biological source: rabbit
Water Solubility: 76.48g/L(24 ºC)
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 100-75-4(CAS DataBase Reference)
IARC: 2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System: N-Nitrosopiperidine (100-75-4)

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Safety

Hazard Codes: T,F
Risk Statements: 25-40-39/23/24/25-23/24/25-11
Safety Statements: 53-23-26-36/37/39-45-36/37-16-9
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: TN2100000
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 100-75-4(Hazardous Substances Data)
Toxicity: LD50 orl-rat: 200 mg/kg ZEKBAI 69,103,67

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB1300842
Product name: Anti-NP1(Nptx1) (C-term) antibody produced in rabbit
Purity: IgG fraction of antiserum, buffered aqueous solution
Packaging: 100μg
Price: $441
Updated: 2024/03/01

Sigma-Aldrich

Product number: 40458
Product name: 1-Nitrosopiperidine solution
Purity: certified reference material, 5000?μg/mL in methanol
Packaging: 1mL
Price: $62.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 40458
Product name: 1-Nitrosopiperidine solution
Purity: certified reference material, 5000 μg/mL in methanol
Packaging: 40458
Price: $47.2
Updated: 2021/12/16

TRC

Product number: N545370
Product name: N-Nitrosopiperidine
Packaging: 500mg
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 156066
Product name: Neuronal Pentraxin I
Packaging: 10ug
Price: $355
Updated: 2021/12/16

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N-NITROSOPIPERIDINE Chemical Properties,Usage,Production

Chemical Properties

light yellow oily liquid

Chemical Properties

N-Nitrosopiperidine is a clear, yellow, oily liquid.

Uses

A carcinogenic nitrosocompound.

Definition

ChEBI: N-nitrosopiperidine is a nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. It has a role as a carcinogenic agent, an apoptosis inducer, a mutagen and an environmental contaminant. It is a nitrosamine and a piperidine.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 36, p. 459, 1988 DOI: 10.1248/cpb.36.459

General Description

Light yellow oil or liquid. May be a carcinogen.

Air & Water Reactions

Water soluble.

Reactivity Profile

N-NITROSOPIPERIDINE may react with strong oxidizing agents, especially peroxyacids. .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOPIPERIDINE emits highly toxic fumes.

Fire Hazard

Flash point data are not available for N-NITROSOPIPERIDINE, but N-NITROSOPIPERIDINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Potential Exposure

N-Nitrosopiperidine is found in some foods and tobacco smoke. Used as a research chemical.

Carcinogenicity

N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

Incompatibilities

Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Reaction with aliphatic amines can release carcinogenic nitrosamines. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light and UV may cause decomposition

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.

N-NITROSOPIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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100-75-4, N-NITROSOPIPERIDINERelated Search:

(R,S)-N-NITROSOANABASINE N-NITROSOPIPERIDINE N-nitroso-3-hydroxypiperidine PIPECOLICACID,1-NITROSO- (R,S)-N-NITROSOANABASINE-D4 4-Methyl-1-nitrosopiperidine,4-METHYL-N-NITROSOPIPERIDINE N-nitroso-4-hydroxypiperidine Nitrosoaphyllinic acid 4-Chloro-1-nitrosopiperidine,4-Chloro-N-nitrosopiperidine N-Nitrosocystisine 2,6-DIMETHYL-1-NITROSOPIPERIDINE,2,6-DIMETHYL-N-NITROSOPIPERIDINE NPIPAC, N-Nitrosopiperidine-2-carboxylic Acid,N-NITROSOPIPERIDINE-2-CARBOXYLIC ACID 2-METHYL-N-NITROSOPIPERIDINE,2-Methyl-1-nitrosopiperidine N-NITROSOPIPERIDINE-D10 4-CARBOXY-1-NITROSOPIPERIDINE 2,2,6,6-Tetramethyl-1-nitrosopiperidine,2,2',6,6'-tetramethyl-N-nitrosopiperidine 1-nitroso-4-phenylpiperidine 3,4-dichloronitrosopiperidine

N-NITROSOPIPERIDINE, 1X1ML, MEOH, 5000UG /ML

1-nitrosopiperidine solution

NITROSOPIPERIDINE

N-NITROSO-4-PIPERIDINE

N-NITROSOAPERIDINE

Piperdine, 1-nitroso-

rcrawastenumberu179

tl266

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47 kDa taipoxin-binding protein

ANTI-NP1(NPTX1) (C-TERM) antibody produced in rabbit

Neuronal pentraxin I

N-Nitrosopiperidine 1g [100-75-4]

NPI

NSC 138

Piperidine, 1-nitroso-

N-NITROSOPIPERIDINE

1-NITROSOPIPERIDINE

1-nitroso-piperidin

hexahydro-n-nitroso-pyridin

Nitrosopiperidin

N-Nitroso-piperidin

N-N-Pip

No-Pip

NPIP

n-pip

Pyridine, hexahydro-N-nitroso-

pyridine,hexahydro-n-nitroso

Rcra waste number U179

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N-Nitrosopiperidine@100 μg/mL in Dichloromethane

N-nitrosopiperidine (NPIP)

N-Nitrospiperidine

N-Nitroso methyl piperidine

N-nitroso-piperidine3,7

N-Nitrosopiperidine in dichloromethane

N-Nitrosopiperidine 100 μg/ml Methanol

100-75-4

C5H10NNO

Carcinogens

BioChemical

Cancer Research

Heterocycles

Mutagenesis Research Chemicals

Nitric Oxide Reagents

NA - NI

N-OAlphabetic

Volatiles/ Semivolatiles

Cancer Research

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