4-CHLORO-6-METHYLQUINAZOLINE

Product Name: 4-CHLORO-6-METHYLQUINAZOLINE
CAS No.: 58421-79-7
Chemical Name: 4-CHLORO-6-METHYLQUINAZOLINE
Synonyms: AKOS BBS-00000251;CHEMBRDG-BB 7188065;IFLAB-BB F1244-0099;4-CHLORO-6-METHYLQUINAZOLINE;Quinazoline, 4-chloro-6-methyl-
CBNumber: CB3377710
Molecular Formula: C9H7ClN2
Formula Weight: 178.62
MOL File: 58421-79-7.mol

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4-CHLORO-6-METHYLQUINAZOLINE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: Off-white to light yellow Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: C374485
Product name: 4-chloro-6-methylquinazoline
Packaging: 10mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: Y9545
Product name: 4-Chloro-6-methylquinazoline
Packaging: 250mg
Price: $166
Updated: 2021/12/16

AK Scientific

Product number: Y9545
Product name: 4-Chloro-6-methylquinazoline
Packaging: 1g
Price: $340
Updated: 2021/12/16

Matrix Scientific

Product number: 084090
Product name: 4-Chloro-6-methylquinazoline
Purity: 97%
Packaging: 1g
Price: $488
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0037227
Product name: 4-CHLORO-6-METHYLQUINAZOLINE
Purity: 95.00%
Packaging: 1G
Price: $896.21
Updated: 2021/12/16

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4-CHLORO-6-METHYLQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

19181-53-4

58421-79-7

The general procedure for the synthesis of 4-chloro-6-methylquinazoline from 6-methyl-4-hydroxyquinazoline was as follows: intermediate 10-b (2.1 g, 13.11 mmol) was dissolved in chloroform (30 ml). Oxalyl chloride (1.97 g, 23.26 mmol) and N,N-dimethylformamide (0.1 ml) were subsequently added. The reaction mixture was heated to 100°C and maintained at this temperature for 3 hours. Upon completion of the reaction, the solvent was removed by evaporation to afford intermediate 10 (1.5 g, 58% yield). Mass spectrometry analysis showed m/z = 179 ([M + H]+).

References

[1] Patent: WO2016/91791, 2016, A1. Location in patent: Page/Page column 20; 21
[2] Patent: WO2016/91774, 2016, A1. Location in patent: Page/Page column 23; 24
[3] Archiv der Pharmazie, 2013, vol. 346, # 1, p. 44 - 52

4-CHLORO-6-METHYLQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-6-METHYLQUINAZOLINE Suppliers

Canada 1 China 72 Germany 1 India 2 Switzerland 1 United Kingdom 2 United States 10 Global 89

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279
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Accela ChemBio Co.,Ltd.

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Shanghai Synthfine Chemical Co.,Ltd

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.

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ShangHai AmK Pharmaceutical Technology Co., Ltd.

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NovoChemy Ltd.

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Shanghai RenYue Chemical Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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58421-79-7, 4-CHLORO-6-METHYLQUINAZOLINERelated Search:

4-CHLORO-2-(2-FLUORO-PHENYL)-6-METHYL-QUINAZOLINE 4-CHLORO-2-TRIFLUOROMETHYL-QUINAZOLINE-6-CARBOXYLIC ACID ETHYL ESTER 4-CHLORO-6-METHYL-2-PHENYL-QUINAZOLINE 2-(4-BROMO-PHENYL)-4-CHLORO-6-METHYL-QUINAZOLINE ethyl 4-chloroquinazoline-6-carboxylate 2,4-DICHLORO-6-METHYLQUINAZOLINE 4-CHLORO-6-METHYLQUINAZOLINE 4-CHLORO-6,8-DIMETHYLQUINAZOLINE 4-CHLORO-2-(4-CHLORO-PHENYL)-6-METHYL-QUINAZOLINE 2,4-DICHLORO-6-(TRIFLUOROMETHYL)-QUINAZOLINE 4-CHLORO-2-(4-METHOXY-PHENYL)-6-METHYL-QUINAZOLINE 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester 4-chloro-6-(trifluoromethyl)quinazoline 4-CHLORO-2-(4-FLUORO-PHENYL)-6-METHYL-QUINAZOLINE 6-(BROMOMETHYL)-4-CHLOROQUINAZOLINE

AKOS BBS-00000251

4-CHLORO-6-METHYLQUINAZOLINE

IFLAB-BB F1244-0099

CHEMBRDG-BB 7188065

Quinazoline, 4-chloro-6-methyl-

58421-79-7