ChemicalBook > CAS DataBase List > 4-CHLORO-6-METHYLQUINAZOLINE

4-CHLORO-6-METHYLQUINAZOLINE

Product Name
4-CHLORO-6-METHYLQUINAZOLINE
CAS No.
58421-79-7
Chemical Name
4-CHLORO-6-METHYLQUINAZOLINE
Synonyms
AKOS BBS-00000251;CHEMBRDG-BB 7188065;IFLAB-BB F1244-0099;4-CHLORO-6-METHYLQUINAZOLINE;Quinazoline, 4-chloro-6-methyl-
CBNumber
CB3377710
Molecular Formula
C9H7ClN2
Formula Weight
178.62
MOL File
58421-79-7.mol
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4-CHLORO-6-METHYLQUINAZOLINE Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
Off-white to light yellow Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
C374485
Product name
4-chloro-6-methylquinazoline
Packaging
10mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
Y9545
Product name
4-Chloro-6-methylquinazoline
Packaging
250mg
Price
$166
Updated
2021/12/16
AK Scientific
Product number
Y9545
Product name
4-Chloro-6-methylquinazoline
Packaging
1g
Price
$340
Updated
2021/12/16
Matrix Scientific
Product number
084090
Product name
4-Chloro-6-methylquinazoline
Purity
97%
Packaging
1g
Price
$488
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0037227
Product name
4-CHLORO-6-METHYLQUINAZOLINE
Purity
95.00%
Packaging
1G
Price
$896.21
Updated
2021/12/16
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4-CHLORO-6-METHYLQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

19181-53-4

58421-79-7

The general procedure for the synthesis of 4-chloro-6-methylquinazoline from 6-methyl-4-hydroxyquinazoline was as follows: intermediate 10-b (2.1 g, 13.11 mmol) was dissolved in chloroform (30 ml). Oxalyl chloride (1.97 g, 23.26 mmol) and N,N-dimethylformamide (0.1 ml) were subsequently added. The reaction mixture was heated to 100°C and maintained at this temperature for 3 hours. Upon completion of the reaction, the solvent was removed by evaporation to afford intermediate 10 (1.5 g, 58% yield). Mass spectrometry analysis showed m/z = 179 ([M + H]+).

References

[1] Patent: WO2016/91791, 2016, A1. Location in patent: Page/Page column 20; 21
[2] Patent: WO2016/91774, 2016, A1. Location in patent: Page/Page column 23; 24
[3] Archiv der Pharmazie, 2013, vol. 346, # 1, p. 44 - 52

4-CHLORO-6-METHYLQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-6-METHYLQUINAZOLINE Suppliers

Canada 1 China 72 Germany 1 India 2 Switzerland 1 United Kingdom 2 United States 10 Global 89
Achemica
Tel
--
Fax
--
Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50

58421-79-7, 4-CHLORO-6-METHYLQUINAZOLINERelated Search:

4-CHLORO-2-(2-FLUORO-PHENYL)-6-METHYL-QUINAZOLINE 4-CHLORO-2-TRIFLUOROMETHYL-QUINAZOLINE-6-CARBOXYLIC ACID ETHYL ESTER 4-CHLORO-6-METHYL-2-PHENYL-QUINAZOLINE 2-(4-BROMO-PHENYL)-4-CHLORO-6-METHYL-QUINAZOLINE ethyl 4-chloroquinazoline-6-carboxylate 2,4-DICHLORO-6-METHYLQUINAZOLINE 4-CHLORO-6-METHYLQUINAZOLINE 4-CHLORO-6,8-DIMETHYLQUINAZOLINE 4-CHLORO-2-(4-CHLORO-PHENYL)-6-METHYL-QUINAZOLINE 2,4-DICHLORO-6-(TRIFLUOROMETHYL)-QUINAZOLINE 4-CHLORO-2-(4-METHOXY-PHENYL)-6-METHYL-QUINAZOLINE 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester 4-chloro-6-(trifluoromethyl)quinazoline 4-CHLORO-2-(4-FLUORO-PHENYL)-6-METHYL-QUINAZOLINE 6-(BROMOMETHYL)-4-CHLOROQUINAZOLINE

  • AKOS BBS-00000251
  • 4-CHLORO-6-METHYLQUINAZOLINE
  • IFLAB-BB F1244-0099
  • CHEMBRDG-BB 7188065
  • Quinazoline, 4-chloro-6-methyl-
  • 58421-79-7