N-TRICOSANOYLTRYPTAMINE
- Product Name
- N-TRICOSANOYLTRYPTAMINE
- CAS No.
- 697226-52-1
- Chemical Name
- N-TRICOSANOYLTRYPTAMINE
- Synonyms
- TAT;MEC17;BR2-SH;TAT-amide;ATAT1 human;TAT(47-57)-amide;N-TRICOSANOYLTRYPTAMINE;Tyrosine aminotransferase;TRICOSANOIC ACID TRYPTAMIDE;alpha tubulin acetyltransferase 1
- CBNumber
- CB3388927
- Molecular Formula
- C64H119N33O13
- Formula Weight
- 1558.84
- MOL File
- Mol file
N-TRICOSANOYLTRYPTAMINE Property
- Melting point:
- 116-120 °C
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- Solid
- color
- White to off-white
- biological source
- rabbit
- Sequence
- Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
Safety
- WGK Germany
- 3
- F
- 10
N-Bromosuccinimide Price
- Product number
- SRP0309
- Product name
- ATAT1 human
- Purity
- recombinant, expressed in <I>E. coli</I>, ≥55% (SDS-PAGE)
- Packaging
- 50 μg
- Price
- $691
- Updated
- 2025/07/31
- Product number
- SAB1303103
- Product name
- ANTI-TAT (CENTER) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 400μL
- Price
- $496
- Updated
- 2025/07/31
- Product number
- SAB1303103
- Product name
- ANTI-TAT (CENTER) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 100μG
- Price
- $423
- Updated
- 2022/05/15
- Product number
- 493419
- Product name
- TAT
- Packaging
- 100ul
- Price
- $499
- Updated
- 2021/12/16
- Product number
- 359141
- Product name
- TAT
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
N-TRICOSANOYLTRYPTAMINE Chemical Properties,Usage,Production
Uses
TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells[1][2].
Biological Activity
ATAT1 (α tubulin acetyltransferase 1) catalyses the acetylation of lysine 40 of α-tubulin and microtubule. ATAT1 expression is essential for microtubule stabilization and mediates cilium formation. Upart from acetylation, αTAT1 interacts with doublecortin (a microtubule associated protein) to degrade microtubules th at are not aligned with acetyltransferase activity. αTAT1 regulates the Wnt1 signalling pathway via β-catenin and promotes tumorigenesis. Overexpression of the ATAT1 gene is observed in colon cancer and is known to contribute to its progression.
References
[1] Xu P, et al. Precise control of apoptosis via gold nanostars for dose dependent photothermal therapy of melanoma. J Mater Chem B. 2019 Nov 28;7(44):6934-6944. DOI:10.1039/c9tb01956a
[2] Okuda-Shinagawa NM, et al. Fluorescent and Photosensitizing Conjugates of Cell-Penetrating Peptide TAT(47-57): Design, Microwave-Assisted Synthesis at 60 °C, and Properties. ACS Omega. 2017 Nov 30;2(11):8156-8166. DOI:10.1021/acsomega.7b01127
N-TRICOSANOYLTRYPTAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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