1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID
- Product Name
- 1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID
- CAS No.
- 115951-16-1
- Chemical Name
- 1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID
- Synonyms
- BOC-NH(1)CHEX-OH;RARECHEM EM WB 0029;BOC-CYCLOHOMOLEUCINE;BOC-HOMOCYCLOLEUCINE;Ambroxol Impurity 125;N-BOC-AMINOCYCLOHEXYLCARBOXYLIC ACID;BOC-1-AMINOCYCLOHEXANECARBOXYLIC ACID;1-(BOC-AMINO)CYCLOHEXANECARBOXYLIC ACID;N-Boc-1-Aminocyclohexanecarboxylic acid;BOC-1-AMINOCYCLOHEXANE-1-CARBOXYLIC ACID
- CBNumber
- CB3390863
- Molecular Formula
- C12H21NO4
- Formula Weight
- 243.3
- MOL File
- 115951-16-1.mol
1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID Property
- Melting point:
- 176-178 °C (dec.)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- color
- White
- BRN
- 4189683
- Major Application
- peptide synthesis
- InChI
- 1S/C12H21NO4/c1-11(2,3)17-10(16)13-12(9(14)15)7-5-4-6-8-12/h4-8H2,1-3H3,(H,13,16)(H,14,15)
- InChIKey
- URBHKVWOYIMKNO-UHFFFAOYSA-N
- SMILES
- CC(C)(C)OC(=O)NC1(CCCCC1)C(O)=O
- CAS DataBase Reference
- 115951-16-1(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29225090
- Storage Class
- 13 - Non Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- 03582
- Product name
- 1-(Boc-amino)cyclohexanecarboxylic acid
- Purity
- ≥98.0% (TLC)
- Packaging
- 1g
- Price
- $42.2
- Updated
- 2022/05/15
- Product number
- B6437
- Product name
- 1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid
- Purity
- min. 97.0 %
- Packaging
- 1G
- Price
- $85
- Updated
- 2025/07/31
- Product number
- B6437
- Product name
- 1-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic Acid
- Purity
- min. 97.0 %
- Packaging
- 5G
- Price
- $256
- Updated
- 2025/07/31
- Product number
- B630010
- Product name
- 1-(Boc-amino)cyclohexanecarboxylic acid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 266542
- Product name
- Boc-1-aminocyclohexane carboxylic acid
- Packaging
- 2g
- Price
- $333
- Updated
- 2021/12/16
1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
peptide synthesis
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
1-tert-butoxycarbonylamide cyclohexanecarboxylic acid was prepared as follows: sodium hydroxide solution (43 mL, 4 mol/L), THF (40 mL) and 1-aminocyclohexanecarboxylic acid (5.0 g, 34.96 mmol) were added to a round-bottomed flask, and di-tert-butyl dicarbonate (9.13 g, 41.96 mmol) was added to the reaction flask at 0 ??C. After dropwise addition was complete, the reaction system was After the dropwise addition, the reaction system was stirred at room temperature overnight. Water (100 mL) was added to the reaction system, acidified with hydrochloric acid (50 mL, 1 mol/L), then extracted with ethyl acetate (50 mL??2), the organic phases were combined, and the organic phases were washed with saturated brine (100 mL??2) and dried with anhydrous sodium sulfate. Filtered, evaporated the solvent under reduced pressure, the crude product was purified by silica gel column chromatography (petroleum ether/ethyl acetate (V/V) = 4/1) to give the white solid title compound 1-tert-butoxycarbonylamide cyclohexanecarboxylic acid (7.3 g, 86%).
1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID manufacturers
- Product
- 1-TERT-BUTOXYCARBONYLAMINO-CYCLOHEXANECARBOXYLIC ACID 115951-16-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-12-18