Muscarinic toxin 1
- Product Name
- Muscarinic toxin 1
- Chemical Name
- Muscarinic toxin 1
- Synonyms
- MT1;MTX1;MEL-1A-R;MT1; MT 1;MUSCARINIC TOXIN 1;Mel1a melatonin receptor;Anti-MTR1A antibody produced in rabbit;Anti-MTNR1A antibody produced in rabbit;Muscarinic Toxin-1 from Dendroaspis angusticeps venom;LEU-THR-CYS-VAL-THR-SER-LYS-SER-ILE-PHE-GLY-ILE-THR-THR-GLU-ASN-CYS-PRO-ASP-GLY-GLN-ASN-LEU-CYS-PHE-LYS-LYS-TRP-TYR-TYR-ILE-VAL-PRO-ARG-TYR-SER-ASP-ILE-THR-TRP-GLY-CYS-ALA-ALA-THR-CYS-PRO-LYS-PRO-THR-ASN-VAL-ARG-GLU-THR-ILE-ARG-CYS-CYS-GLU-THR-ASP-LYS-CYS-ASN-GLU
- CBNumber
- CB3392337
- Formula Weight
- 0
- MOL File
- Mol file
Muscarinic toxin 1 Property
- storage temp.
- −20°C
- form
- lyophilized powder
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SAB4501929
- Product name
- Anti-MTR1A antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μG
- Price
- $485
- Updated
- 2023/01/07
- Product number
- orb599212
- Product name
- MTX1
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
- Product number
- DC10023
- Product name
- MT-1
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- DC10023
- Product name
- MT-1
- Purity
- >98%
- Packaging
- 250mg
- Price
- $2000
- Updated
- 2021/12/16
Muscarinic toxin 1 Chemical Properties,Usage,Production
Origin
Muscarinic toxin 1 was originally isolated from mamba venom and consists of 65 to 66 amino acid residues with four intramolecular disulfide bonds. Recent studies have shown that activation of muscarinic acetylcholine receptors regulates the metabolism of β-amyloid precursor proteins, and that muscarinic agonists reduce the production of amyloid-β proteins.
Biological Functions
Muscarinic toxin 1 has non-competitive interactions with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC50=2.3 nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B) and alpha-2c (ADRA2C) adrenergic receptors. Reversibly binds to the M1 (CHRM1) muscarinic acetylcholine receptor, probably through interaction with the orthosteric site. Also has slightly weaker effects on M3 (CHRM3) and M4 (CHRM4) receptors. The order of potency is ADRA2B>>CHRM1>ADRA1A>ADRA1B>ADRA2C/CHRM4 (PubMed:24793485).
Advantages
Muscarinic toxins isolated from the venom of Dendroaspis snakes may interact with a high affinity, large selectivity and various functional properties with muscarinic receptors.
Muscarinic toxin 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Muscarinic toxin 1 Suppliers
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View Lastest Price from Muscarinic toxin 1 manufacturers
- Product
- MT-1
- Price
- US $10.00/box
- Min. Order
- 1box
- Purity
- 99
- Supply Ability
- in stock
- Release date
- 2025-10-15
- Product
- MT-1
- Price
- US $40.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 1000box/month
- Release date
- 2025-06-18
- Product
- MT-1
- Price
- US $30.00-20.00/Box
- Min. Order
- 1Box
- Purity
- 99%
- Supply Ability
- 1000 boxs
- Release date
- 2024-05-29