N-Acetyl-L-methionine

Identification Test Content Analysis Toxicity Grade Acute Toxicity Use Quantity

Product Name: N-Acetyl-L-methionine
CAS No.: 65-82-7
Chemical Name: N-Acetyl-L-methionine
Synonyms: NAM;N-Acetylmethionine;AC-MET-OH;ACETYL-L-METHIONINE;N-ACETYL-L-METHIONINE:AC-MET-OH;methionin;n-acetyl-l-methionin;N-AC-L-MET;Ac-L-Met-OH;AC-METHIONINE
CBNumber: CB3394487
Molecular Formula: C7H13NO3S
Formula Weight: 191.25
MOL File: 65-82-7.mol

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N-Acetyl-L-methionine Property

Melting point:: 103-106 °C(lit.)
alpha: -20 º (c=4 H2O)
Boiling point:: 235 °C(Press: 12 Torr)
Density: 1.2684 (rough estimate)
refractive index: -21 ° (C=1, H2O)
storage temp.: Sealed in dry,Room Temperature
solubility: methanol: soluble100mg/mL, clear, colorless
pka: 3.50±0.10(Predicted)
form: Solid
color: White to Off-White
optical activity: [α]20/D -21.0±1.0°, c = 1% in H2O
Merck: 14,96
BRN: 1725552
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: XUYPXLNMDZIRQH-LURJTMIESA-N
LogP: -0.885 (est)
CAS DataBase Reference: 65-82-7(CAS DataBase Reference)
NIST Chemistry Reference: N-acetylmethionine(65-82-7)
EPA Substance Registry System: L-Methionine, N-acetyl- (65-82-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
RTECS: PD0480000
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29309070

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 01310
Product name: N-Acetyl-L-methionine
Purity: ≥98.5% (T)
Packaging: 5g
Price: $54.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 01310
Product name: N-Acetyl-L-methionine
Purity: ≥98.5% (T)
Packaging: 25g
Price: $207
Updated: 2024/03/01

TCI Chemical

Product number: A2056
Product name: N-Acetyl-L-methionine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: A2056
Product name: N-Acetyl-L-methionine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $34
Updated: 2024/03/01

Alfa Aesar

Product number: B24312
Product name: N-Acetyl-L-methionine, 99%
Packaging: 5g
Price: $41.65
Updated: 2024/03/01

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N-Acetyl-L-methionine Chemical Properties,Usage,Production

Identification Test

Take a sample of 250mg, get it dissolved it in 2.5ml isopropyl alcohol and get it diluted with water to 25ml. Take this liquid of 10ml and get it diluted with water to 100m1. Then take the liquid of 0.5,30 and 50μ1 after two dilutions. Drop it at the place with a distance of 2cm from the bottom edge of the thin-layer chromatographic plate. The plate is coated with silica gel (Namely, 20cm * 20cm Brinkman silica gel of 60.250nm, or the equivalent). In a sealed and balanced thin-layered chromatography expansion tank, The chromatography was splayed out by 10cm, and the developer was composed of n-butanol and the mixture of acetic acid and water in the proportion 75：20=20.

Dry the plate overnight. Then spray the chromatography plate with a new iodoplatinate solution mixed with 10 percent chloroplatinic acid of 3ml, water of 97ml and 6 percent potassium iodide solution of 100ml. The sample shall be formed - a separate color spot with a Rf value of 0.67~0.1

Content Analysis

Weigh accurately about 250mg sample and put it in a flask with glass stopper. Add 100ml water, 5g dipotassium hydrogen phosphate, 2g potassium dihydrogen phosphate and 2g potassium iodide. Get it fully mixed and dissolved, plus 0. 1mol/L iodine solution of 50.0m1. Then stopper it and blend it. Leave it stand for 30 minutes and titrate excess iodine with 0.1mol / L sodium thiosulfate. Meanwhile conduct blank titration experiment. Iodine solution per Ml 0.1mol/L equals to this product (C7H13NO3S) 9.563mg.

Toxicity Grade

Safe for food(FDA，§172．372，2000).

Acute Toxicity

Vein - mouse LD50: 435 mg / kg

Use Quantity

Account for 3.1% of the total protein content in food (Calculated by free L- methionine).
It shall not be used for infant food and food containing adding nitrite / nitrate (FDA, 172.3722000).

Chemical Properties

white crystals

Uses

N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-?stored platelets.

Definition

ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.

Safety Profile

Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,.

Purification Methods

Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]

N-Acetyl-L-methionine Preparation Products And Raw materials

Raw materials

L-Methionine

Preparation Products

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View Lastest Price from N-Acetyl-L-methionine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: N-Acetyl-L-methionine 65-82-7
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%-100.5% AJI
Supply Ability: 1000kg
Release date: 2021-09-22

airuikechemical co., ltd.

Product: N-Acetyl-L-methionine 65-82-7
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 20 tons
Release date: 2024-03-29

Hebei Weibang Biotechnology Co., Ltd

Product: N-Acetyl-L-methionine 65-82-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-30

65-82-7, N-Acetyl-L-methionineRelated Search:

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Factory Direct Sale N-Acetyl-L-Methionine CAS?65-82-7

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TIANFUCHEM--65-82-7--N-Acetyl-L-methionine

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Allyl heptanoate 142-19-8

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Methionine EP Impurity C as (S)-Enantiomer

Methionine Impurity C as (S)-Enantiomer

65-82-7

C7H13NO3S

CH3SCH2CH2CH15NHCOCH3CO2H

CH3SCH2CH2CHNHCOCH3CO2H

Amino Acid Derivatives

CARBOXYLIC ACID

Methionine

Peptide Synthesis