D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE

Product Name: D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE
CAS No.: 75590-17-9
Chemical Name: D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE
Synonyms: DVal-Phe-Lys-CMK;PLASMIN INHIBITOR, 2HCL;valyl-phenylalanyl-lysine chloromethyl ketone;D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE;L-Phenylalaninamide, D-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-
CBNumber: CB3399806
Molecular Formula: C21H33ClN4O3
Formula Weight: 424.96
MOL File: 75590-17-9.mol

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D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Property

Boiling point:: 707.0±60.0 °C(Predicted)
Density: 1.160±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 5mg/mL
pka: 13.06±0.46(Predicted)
form: lyophilized solid
color: off-white
Sequence: {d-Val}-Phe-Lys-{CMK}

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Hazard and Precautionary Statements (GHS)

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D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) can inhibit plasmin activity[1].

Biological Activity

Cell permeable: no', 'Primary Target
Human plasmin', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 100 pM for human plasmin

References

[1] F Laube, et al. Cell surface antigens in renal tumour cells: detection by immunoluminescence and enzymatic analysis. Br J Cancer. 2001 Sep 14;85(6):924-9. DOI:10.1054/bjoc.2001.2004

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Suppliers

China 3 United Kingdom 2 United States 2 Global 7

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
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Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
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Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
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75590-17-9, D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDERelated Search:

PLASMIN (R)-(+)-1,2-Diaminopropane dihydrochloride H-D-ALA-GLY-NH2 HCL N-(1-methyl-2-oxopropyl)acetamide D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE (R)-(-)-2-AMINOBUTANAMIDE HYDROCHLORIDE, 97% H-GLY-PHE-NH2 HCL N-METHYL-3-CHLOROPROPYLAMINE HYDROCHLORIDE (2R)-2-Aminopropanamide hydrochloride H-D-VAL-NH2 HCL

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE

PLASMIN INHIBITOR, 2HCL

valyl-phenylalanyl-lysine chloromethyl ketone

L-Phenylalaninamide, D-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-

DVal-Phe-Lys-CMK

75590-17-9

C21H33ClN4O3HCl