ChemicalBook > CAS DataBase List > (2R)-2-Aminopropanamide hydrochloride

(2R)-2-Aminopropanamide hydrochloride

Product Name
(2R)-2-Aminopropanamide hydrochloride
CAS No.
71810-97-4
Chemical Name
(2R)-2-Aminopropanamide hydrochloride
Synonyms
H-D-ALA-NH2 HCL;D-ALANINAMIDE HYDROCHLORIDE;H-D-Ala-NH;D-Ala-NH2 HCl;D-AlaninamideHCl;D-ALANINEAMIDEHCL;D-ALANINE-NH2 HCL;Letermovir Impurity 19;H-D-Ala-NH2 hydrochloride;Safinamide Impurity SM3-E
CBNumber
CB9268535
Molecular Formula
C3H9ClN2O
Formula Weight
124.57
MOL File
71810-97-4.mol
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(2R)-2-Aminopropanamide hydrochloride Property

Melting point:
169 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in water or 1% acetic acid
form 
Powder
color 
White
Water Solubility 
Soluble in 1% acetic acid and water.
InChI
InChI=1/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/s3
InChIKey
FIAINKIUSZGVGX-NNUCSGGJNA-N
SMILES
[C@@H](N)(C)C(=O)N.Cl |&1:0,r|
CAS DataBase Reference
71810-97-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
22-26-36/37/39
Hazard Note 
Harmful
HS Code 
2922390090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR22614
Product name
(2R)-2-Aminopropanamidehydrochloride
Purity
97%
Packaging
25g
Price
$116
Updated
2021/12/16
SynQuest Laboratories
Product number
4158-5-X5
Product name
(2R)-2-Aminopropanamide hydrochloride
Purity
97%
Packaging
25g
Price
$128
Updated
2021/12/16
Chem-Impex
Product number
03011
Product name
D-Alanineamidehydrochloride,99%(HPLC)
Purity
99%(HPLC)
Packaging
1G
Price
$16.8
Updated
2021/12/16
AK Scientific
Product number
W8072
Product name
(R)-2-Aminopropanamidehydrochloride
Packaging
1g
Price
$18
Updated
2021/12/16
Apolloscientific
Product number
OR22614
Product name
(2R)-2-Aminopropanamidehydrochloride
Purity
97%
Packaging
5g
Price
$40
Updated
2021/12/16
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(2R)-2-Aminopropanamide hydrochloride Chemical Properties,Usage,Production

Uses

D-Alaninamide hydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.

Synthesis

1336-21-6

3744-87-4

541-41-3

71810-97-4

The general procedure for the synthesis of D-alaninamide hydrochloride from ammonia, (tert-butoxycarbonyl)alanine and ethyl chloroformate is as follows: 1. Boc-D-alanine (5.0 g, 26.43 mmol) was dissolved in anhydrous THF (100 mL). 2. triethylamine (4 mL, 2.91 g, 28.76 mmol) was added to the solution, followed by slow dropwise addition of ethyl chloroformate (2.5 mL, 2.951 g, 27.19 mmol). 3. The reaction mixture was placed in a carbon tetrachloride/dry ice cold bath with continuous stirring for about 30 minutes. 4. Concentrated ammonium hydroxide solution (5 mL, 74.0 mmol) was added, then the reaction mixture was transferred to a refrigerator and allowed to stand overnight. 5. Upon completion of the reaction, the solvent was removed by vacuum evaporation and the residue was dissolved in ethyl acetate. 6. The ethyl acetate layer was washed using saturated sodium carbonate solution and water, followed by drying the organic phase with anhydrous magnesium sulfate. 7. The desiccant was removed by filtration and the solvent was evaporated to obtain the crude product. 8. The crude product was treated with saturated hydrochloric acid/dioxane solution for 1 hour at room temperature. 9. The dioxane was removed by vacuum evaporation and the residue was dissolved in a small amount of methanol and precipitated by the addition of ether to give D-alaninamide hydrochloride (2.5 g, 76% yield).

References

[1] Patent: US5438118, 1995, A

(2R)-2-Aminopropanamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R)-2-Aminopropanamide hydrochloride Suppliers

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
023-13650506873 19923294409
Email
xingcanyaoye@sina.com
Country
China
ProdList
1604
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1390
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62
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
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66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
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60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
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View Lastest Price from (2R)-2-Aminopropanamide hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
(2R)-2-Aminopropanamide hydrochloride 71810-97-4
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
500kg
Release date
2021-10-08
Wuhan Boyuan Import & Export Co., LTD
Product
(2R)-2-Aminopropanamide hydrochloride 71810-97-4
Price
US $30.00-37.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
1000
Release date
2023-02-17
Hangzhou ICH Biofarm Co., Ltd
Product
D-Alanine amide·hydrochloride salt 71810-97-4
Price
US $0.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
200kg
Release date
2023-06-26

71810-97-4, (2R)-2-Aminopropanamide hydrochlorideRelated Search:


  • (2R)-2-AMINOPROPANAMIDE HYDROCHLORIDE
  • H-D-ALA-NH2 HCL
  • D-ALANINEAMIDEHCL
  • D-ALANINE AMIDE HYDROCHLORIDE
  • D-ALANINAMIDE HYDROCHLORIDE
  • D-ALANINE-NH2 HCL
  • D-Ala-NH2 HCl
  • D-AlaninamideHCl
  • H-D-Ala-NH2HCl(D-AlanineamideHCl)
  • H-D-Ala-NH2HCl(D-Alanineamidehydrochloride)
  • (R)-2-Aminopropanamide hydrochloride
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  • (2R)-2-Aminopropamide hydrochloride
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  • (R)-2-AMinopropanaMide hydrochloride, 95+%
  • H-D-Ala-NH2 hydrochloride
  • (2R)-2-Aminopropanamide hydrochloride USP/EP/BP
  • Propanamide, 2-amino-, hydrochloride (1:1), (2R)-
  • (2R)-2-amino-Propanamide hydrochloride (1:1)
  • D-Alanine amide·hydrochloride salt
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  • Safinamide Impurity SM3-E
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  • 71810-97-4
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  • C3H8N2OClH
  • Alanine [Ala, A]
  • Amino Acids