(2R)-2-Aminopropanamide hydrochloride
- Product Name
- (2R)-2-Aminopropanamide hydrochloride
- CAS No.
- 71810-97-4
- Chemical Name
- (2R)-2-Aminopropanamide hydrochloride
- Synonyms
- H-D-ALA-NH2 HCL;D-ALANINAMIDE HYDROCHLORIDE;H-D-Ala-NH;D-Ala-NH2 HCl;D-AlaninamideHCl;D-ALANINEAMIDEHCL;D-ALANINE-NH2 HCL;Letermovir Impurity 19;H-D-Ala-NH2 hydrochloride;Safinamide Impurity SM3-E
- CBNumber
- CB9268535
- Molecular Formula
- C3H9ClN2O
- Formula Weight
- 124.57
- MOL File
- 71810-97-4.mol
(2R)-2-Aminopropanamide hydrochloride Property
- Melting point:
- 169 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in water or 1% acetic acid
- form
- Powder
- color
- White
- Water Solubility
- Soluble in 1% acetic acid and water.
- InChI
- InChI=1/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/s3
- InChIKey
- FIAINKIUSZGVGX-NNUCSGGJNA-N
- SMILES
- [C@@H](N)(C)C(=O)N.Cl |&1:0,r|
- CAS DataBase Reference
- 71810-97-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-26-36/37/39
- Hazard Note
- Harmful
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- OR22614
- Product name
- (2R)-2-Aminopropanamidehydrochloride
- Purity
- 97%
- Packaging
- 25g
- Price
- $116
- Updated
- 2021/12/16
- Product number
- 4158-5-X5
- Product name
- (2R)-2-Aminopropanamide hydrochloride
- Purity
- 97%
- Packaging
- 25g
- Price
- $128
- Updated
- 2021/12/16
- Product number
- 03011
- Product name
- D-Alanineamidehydrochloride,99%(HPLC)
- Purity
- 99%(HPLC)
- Packaging
- 1G
- Price
- $16.8
- Updated
- 2021/12/16
- Product number
- W8072
- Product name
- (R)-2-Aminopropanamidehydrochloride
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
- Product number
- OR22614
- Product name
- (2R)-2-Aminopropanamidehydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $40
- Updated
- 2021/12/16
(2R)-2-Aminopropanamide hydrochloride Chemical Properties,Usage,Production
Uses
D-Alaninamide hydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.
Synthesis
1336-21-6
3744-87-4
541-41-3
71810-97-4
The general procedure for the synthesis of D-alaninamide hydrochloride from ammonia, (tert-butoxycarbonyl)alanine and ethyl chloroformate is as follows: 1. Boc-D-alanine (5.0 g, 26.43 mmol) was dissolved in anhydrous THF (100 mL). 2. triethylamine (4 mL, 2.91 g, 28.76 mmol) was added to the solution, followed by slow dropwise addition of ethyl chloroformate (2.5 mL, 2.951 g, 27.19 mmol). 3. The reaction mixture was placed in a carbon tetrachloride/dry ice cold bath with continuous stirring for about 30 minutes. 4. Concentrated ammonium hydroxide solution (5 mL, 74.0 mmol) was added, then the reaction mixture was transferred to a refrigerator and allowed to stand overnight. 5. Upon completion of the reaction, the solvent was removed by vacuum evaporation and the residue was dissolved in ethyl acetate. 6. The ethyl acetate layer was washed using saturated sodium carbonate solution and water, followed by drying the organic phase with anhydrous magnesium sulfate. 7. The desiccant was removed by filtration and the solvent was evaporated to obtain the crude product. 8. The crude product was treated with saturated hydrochloric acid/dioxane solution for 1 hour at room temperature. 9. The dioxane was removed by vacuum evaporation and the residue was dissolved in a small amount of methanol and precipitated by the addition of ether to give D-alaninamide hydrochloride (2.5 g, 76% yield).
References
[1] Patent: US5438118, 1995, A
(2R)-2-Aminopropanamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2R)-2-Aminopropanamide hydrochloride manufacturers
- Product
- (2R)-2-Aminopropanamide hydrochloride 71810-97-4
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2021-10-08
- Product
- (2R)-2-Aminopropanamide hydrochloride 71810-97-4
- Price
- US $30.00-37.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 1000
- Release date
- 2023-02-17
- Product
- D-Alanine amide·hydrochloride salt 71810-97-4
- Price
- US $0.00/Box
- Min. Order
- 1Box
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2023-06-26