Levomepromazine hydrochloride
- Product Name
- Levomepromazine hydrochloride
- CAS No.
- 1236-99-3
- Chemical Name
- Levomepromazine hydrochloride
- Synonyms
- Einecs 214-978-3;LevomepromazineHCl;7044 Rp hydrochloride;Levomepromazinium chloride;Levopromazine hydrochloride;Levomepromazine hydrochloride;Levomepromazine D6 hydrochloride;Levomepromazine hydrochloride CRS;Levomepromazine hydrochloride(HCl);Levomepromazine hydrochloride [usan:jan]
- CBNumber
- CB0888820
- Molecular Formula
- C19H24N2OS.ClH
- Formula Weight
- 364.93
- MOL File
- 1236-99-3.mol
Levomepromazine hydrochloride Property
- storage temp.
- 2-8°C
Safety
- Toxicity
- LD50 oral in mouse: 380mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- L0500000
- Product name
- Levomepromazine hydrochloride
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- l0500000
- Price
- $153
- Updated
- 2024/03/01
- Product number
- INB0000731
- Product name
- LEVOMEPROMAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $909.56
- Updated
- 2021/12/16
Levomepromazine hydrochloride Chemical Properties,Usage,Production
Originator
Levoprome ,Lederle,US,1966
Uses
Analgesic (central nervous system depressant).
Definition
ChEBI: Levomepromazine hydrochloride is a member of phenothiazines.
Manufacturing Process
95% sodamide (2.33 g) is added to a boiling solution of 3- methoxyphenthiazine (12 g) in anhydrous xylene (150 cc) and the mixture is heated with agitation under reflux for 1? hours. A solution of 1- dimethylamino-2-methyl-3-chloropropane (8.2 g) in anhydrous xylene (90 cc) is then run in over a period of 45 minutes while the reaction temperature is maintained and heating under reflux is continued for 18 hours.
After cooling, the reaction mixture is agitated with a mixture of water (40 cc) and a normal solution of methanesulfonic acid (70 cc), the xylene layer is removed and the acid liquors are washed with ether (200 cc). The aqueous phase is then made alkaline with sodium hydroxide (d = 1.33; 10 cc) and the liberated base is extracted with ether. The ethereal solution is dried over anhydrous potassium carbonate and concentrated at normal pressure. On distillation of the residue under reduced pressure 3-(3-methoxy-10- phenthiazinyl)-2-methyl-1-dimethylaminopropane (11.3 g) is obtained, MP 103°C, BP 182° to 191°C/0.15 mm Hg. The hydrochloride prepared in isopropanol melts at about 90°C.
brand name
Nozinan (Aventis).
Therapeutic Function
Analgesic
Levomepromazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Levomepromazine hydrochloride manufacturers
- Product
- Levomepromazine hydrochloride 1236-99-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000Kg
- Release date
- 2024-08-08