ChemicalBook > CAS DataBase List > Levomepromazine hydrochloride

Levomepromazine hydrochloride

Product Name
Levomepromazine hydrochloride
CAS No.
1236-99-3
Chemical Name
Levomepromazine hydrochloride
Synonyms
Einecs 214-978-3;LevomepromazineHCl;7044 Rp hydrochloride;Levomepromazinium chloride;Levopromazine hydrochloride;Levomepromazine hydrochloride;Levomepromazine D6 hydrochloride;Levomepromazine hydrochloride CRS;Levomepromazine hydrochloride(HCl);Levomepromazine hydrochloride [usan:jan]
CBNumber
CB0888820
Molecular Formula
C19H24N2OS.ClH
Formula Weight
364.93
MOL File
1236-99-3.mol
More
Less

Levomepromazine hydrochloride Property

storage temp. 
2-8°C
More
Less

Safety

Toxicity
LD50 oral in mouse: 380mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0500000
Product name
Levomepromazine hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
l0500000
Price
$153
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
INB0000731
Product name
LEVOMEPROMAZINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$909.56
Updated
2021/12/16
More
Less

Levomepromazine hydrochloride Chemical Properties,Usage,Production

Originator

Levoprome ,Lederle,US,1966

Uses

Analgesic (central nervous system depressant).

Definition

ChEBI: Levomepromazine hydrochloride is a member of phenothiazines.

Manufacturing Process

95% sodamide (2.33 g) is added to a boiling solution of 3- methoxyphenthiazine (12 g) in anhydrous xylene (150 cc) and the mixture is heated with agitation under reflux for 1? hours. A solution of 1- dimethylamino-2-methyl-3-chloropropane (8.2 g) in anhydrous xylene (90 cc) is then run in over a period of 45 minutes while the reaction temperature is maintained and heating under reflux is continued for 18 hours.
After cooling, the reaction mixture is agitated with a mixture of water (40 cc) and a normal solution of methanesulfonic acid (70 cc), the xylene layer is removed and the acid liquors are washed with ether (200 cc). The aqueous phase is then made alkaline with sodium hydroxide (d = 1.33; 10 cc) and the liberated base is extracted with ether. The ethereal solution is dried over anhydrous potassium carbonate and concentrated at normal pressure. On distillation of the residue under reduced pressure 3-(3-methoxy-10- phenthiazinyl)-2-methyl-1-dimethylaminopropane (11.3 g) is obtained, MP 103°C, BP 182° to 191°C/0.15 mm Hg. The hydrochloride prepared in isopropanol melts at about 90°C.

brand name

Nozinan (Aventis).

Therapeutic Function

Analgesic

Levomepromazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Levomepromazine hydrochloride Suppliers

ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 15920483169
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17944
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9590
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
132020
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9589
Advantage
58
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
AFINE CHEMICALS LIMITED
Tel
0571-85134551
Fax
008657185134895
Email
info@afinechem.com
Country
CHINA
ProdList
15377
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23931
Advantage
58
Amel Pharmatech Corporation
Tel
888-4366503
Fax
888-502-1736
Email
sales@amelpharmatech.com
Country
China
ProdList
5351
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
47465
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
10787
Advantage
58

1236-99-3, Levomepromazine hydrochlorideRelated Search:


  • LevomepromazineHCl
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, monohydrochloride, (bR)- (9CI)
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, monohydrochloride, (R)-
  • 10-(3-Dimethylamino-2-methylpropyl)-2-methoxyphenothiazine hydrochloride
  • Levomepromazine hydrochloride
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, monohydrochloride, (R)- (9ci)
  • 7044 Rp hydrochloride
  • Einecs 214-978-3
  • Levomepromazine hydrochloride [usan:jan]
  • Levomepromazinium chloride
  • Levopromazine hydrochloride
  • (R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropylamine hydrochloride
  • 3-(2-methoxy-10-phenothiazinyl)-N,N,2-trimethyl-1-propanamine
  • Levomepromazine hydrochloride CRS
  • Levomepromazine D6 hydrochloride
  • TIANFU-CHEM CAS NO.1236-99-3 Levomepromazine hydrochloride
  • Levomepromazine hydrochloride(HCl)
  • 1236-99-3
  • C19H24N2OSHCl