Levomepromazine hydrochloride

Product Name: Levomepromazine hydrochloride
CAS No.: 1236-99-3
Chemical Name: Levomepromazine hydrochloride
Synonyms: Einecs 214-978-3;LevomepromazineHCl;7044 Rp hydrochloride;Levomepromazinium chloride;Levopromazine hydrochloride;Levomepromazine hydrochloride;Levomepromazine D6 hydrochloride;Levomepromazine hydrochloride CRS;Levomepromazine hydrochloride(HCl);Levomepromazine hydrochloride [usan:jan]
CBNumber: CB0888820
Molecular Formula: C19H24N2OS.ClH
Formula Weight: 364.93
MOL File: 1236-99-3.mol

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Levomepromazine hydrochloride Property

storage temp.: 2-8°C

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Safety

Toxicity: LD50 oral in mouse: 380mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L0500000
Product name: Levomepromazine hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: l0500000
Price: $153
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: INB0000731
Product name: LEVOMEPROMAZINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $909.56
Updated: 2021/12/16

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Levomepromazine hydrochloride Chemical Properties,Usage,Production

Originator

Levoprome ,Lederle,US,1966

Uses

Analgesic (central nervous system depressant).

Definition

ChEBI: Levomepromazine hydrochloride is a member of phenothiazines.

Manufacturing Process

95% sodamide (2.33 g) is added to a boiling solution of 3- methoxyphenthiazine (12 g) in anhydrous xylene (150 cc) and the mixture is heated with agitation under reflux for 1? hours. A solution of 1- dimethylamino-2-methyl-3-chloropropane (8.2 g) in anhydrous xylene (90 cc) is then run in over a period of 45 minutes while the reaction temperature is maintained and heating under reflux is continued for 18 hours.
After cooling, the reaction mixture is agitated with a mixture of water (40 cc) and a normal solution of methanesulfonic acid (70 cc), the xylene layer is removed and the acid liquors are washed with ether (200 cc). The aqueous phase is then made alkaline with sodium hydroxide (d = 1.33; 10 cc) and the liberated base is extracted with ether. The ethereal solution is dried over anhydrous potassium carbonate and concentrated at normal pressure. On distillation of the residue under reduced pressure 3-(3-methoxy-10- phenthiazinyl)-2-methyl-1-dimethylaminopropane (11.3 g) is obtained, MP 103°C, BP 182° to 191°C/0.15 mm Hg. The hydrochloride prepared in isopropanol melts at about 90°C.

brand name

Nozinan (Aventis).

Therapeutic Function

Analgesic

Levomepromazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Levomepromazine hydrochloride Suppliers

China 22 France 1 Germany 1 India 4 United States 5 Global 33

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View Lastest Price from Levomepromazine hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Levomepromazine hydrochloride 1236-99-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000Kg
Release date: 2024-08-08

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Einecs 214-978-3

Levomepromazine hydrochloride [usan:jan]

Levomepromazinium chloride

Levopromazine hydrochloride

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Levomepromazine hydrochloride CRS

Levomepromazine D6 hydrochloride

TIANFU-CHEM CAS NO.1236-99-3 Levomepromazine hydrochloride

Levomepromazine hydrochloride(HCl)

1236-99-3

C19H24N2OSHCl