LINAMARIN Property

Melting point:

142-143°C

alpha 

D18 -29°

Boiling point:

390.28°C (rough estimate)

Density 

1.2868 (rough estimate)

refractive index 

1.4610 (estimate)

storage temp. 

2-8°C

solubility 

Soluble in DMSO, Methanol, and Ethanol

form 

solid

pka

12.73±0.70(Predicted)

color 

White or off-white

optical activity

[α]/D -26.5±2.0°, c = 1 in H2O

Stability:

Acid Sensitive

Safety

Hazard Codes 

Xn

Risk Statements 

20/22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

TZ4850000

HS Code 

29400090

Hazardous Substances Data

554-35-8(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

LINAMARIN Chemical Properties,Usage,Production

Description

Linamarin is a glucoside of acetone cyanohydrin found in the leaves and roots of cassava, lima beans, and flax. It is thought to function in the transport of nitrogen from plant leaves to roots in young plants but also serves as a plant defense mechanism. Linamarin is converted to toxic hydrocyanic acid or prussic acid when it comes into contact with linamarase, an enzyme that is released when the cells of cassava roots are ruptured.

Chemical Properties

White Crystalline Solid

Uses

Can be found in the seed skins and embryos of flax.

Definition

ChEBI: Linamarin is a beta-D-glucoside. It is functionally related to a 2-hydroxy-2-methylpropanenitrile.

References

1) Jensen?et al.?(2011),?Convergent evolution in biosynthesis if cyanogenic defense compounds in plants; Nat. Commun.,?2?273 2) Rivadeneyra?et al. (2013),?Neurotoxic effect of linamarin in rats associated with cassava (Manihot esculenta Crantz) consumption; Food Chem. Toxicol.,?59?230 3) Kimani?et al. (2014),?Memory deficits associated with sublethal cyanide poisoning relative to cyanate toxicity in rodents; Metab. Brain Dis.,?29?105